GHK-Cu Aggregation in Reconstituted Vials

Haven't noticed anything like that in my own vials. Been using GHK every day for five or six months. Which bac water are you using? I've tried a couple brands myself.

Which bac water brand did you go with? I think this might be related to pH. Since the vials came from different places but the bac water was the same, that could explain it.

Can you clarify what you meant about adding more bac water and nothing else happening? Did the stuff at the bottom dissolve after that, or did it stay clumped?

It calming down after extra bac water suggests it's about how concentrated it is, not the peptide spoiling. Putting 100mg GHK-Cu into a small amount of liquid is a lot, and these copper peptides can come out of solution if kept cold and strong, or if pH changes. Starting with more dilution avoids the problem. If something remains at the bottom even after warming the vial in your hand, better to discard it than risk using it.

To help narrow this down, could you share more details like how much bac water you used for the 100mg GHK-Cu, which brand, and whether it was plain or saline version? Also, exactly what occurred when you added the extra bac water? Haven't come across this before, but thanks for mentioning it. I've been using GHK-Cu myself for several months with 50mg vials, usually mixing in about 6mL of bac water or saline bac water to lessen the sting, and haven't run into aggregation. I've tried a few different bac waters including saline versions.

Used 100mg GHK-Cu vials from multiple sources over the past eight months without ever seeing this happen. I always mix them with 10ml of bac water.

Sorry to hear that. I've come across similar pictures elsewhere and they often trace back to the bac water used. Some bac waters seem more reliable than others. Because I was worried about stinging from GHK-Cu, I mixed my 50mg with 10ml of bac water.

I've mixed 100mg amounts using anywhere from 10 to 30 mL of bac water since April and never ran into that kind of problem. Both the liquid and vial were at room temperature during mixing, though I'm not sure if that matters. It's odd it only showed up nearly a week later.

I'm mixing 100mg amounts with 3ml of bac water and haven't seen any problems so far.

I only use pharmacy-grade bac water and this showed up for several others besides me. Most who ran into it were using the same common brand. The vial mixes fine at first, but after a week of use those clumps appear at the bottom. Adding extra bac water and turning the vial makes them go away. It looks like some kind of reaction, though I haven't found an explanation for why.

These came from separate vials and different sources. Only one of the photos is mine, the rest from two other places that used different bac water. It's not limited to my case; others have seen the same thing.

From the affected vial that had 3ml bac water with 100mg, I pulled half out, filtered it into a fresh vial, then added another 0.4ml from the same bac bottle to the remaining solution that still held about 40mg. The clumps cleared once the extra liquid went in. I then stored that vial in the fridge for over three weeks without touching or shaking it and nothing formed.

I quickly lost interest in the 100mg size. For most items larger amounts are convenient, but I dilute these enough to split the filtered mix across two 3ml sterile vials using 6ml total bac water. Never saw anything like what was shown. I'd suggest anyone considering these to pick the 50mg size instead. I still have a bunch of the 100s sitting because I switched to 50s for actual use.

I ran into chunky material recently as well. In my case I was combining it with another peptide in the same cartridges. Adjusting the ratio fixed it for me, though I'm not sure if the root cause was pH, concentration, or something else. Since it happened with multiple brands of bac water, concentration seems the most likely.

Not happening in my vials. Everything stays fully mixed with no clumps at all.

Another method I tested was reconstituting both the KPV and the KLOW together using one 5ml syringe. Because I filter into 3ml sterile vials this took two of them. I do have 5ml sterile vials but they won't fit in my 20 slot case for ready vials. I pulled 5ml of BAC into the syringe and added roughly 3ml to the KLOW and the remaining 2ml to the KPV. After both had fully dissolved I drew the KLOW solution into the syringe first, then drew the KPV into the same syringe so the two could mix. The blue color makes it easy to watch them combine. Before I always pulled each into separate syringes and then had to guess the amounts going into each vial to keep them equal, which bothered me when I set them next to each other and saw small volume differences. Mixing everything in the one big syringe first meant the amounts going into the vials didn't matter for evenness.

I prepared a batch of that KLOW mixture with GHK-B for my father by combining ten milligrams of the GHK-B into eighty milligrams of the KLOW. He mentioned it produced zero irritation at all.

How long have you been on the 3mg? I've been using the GHK-cu at 3mg for a couple of months now, and before that it was the usual 2mg with breaks in between. My main question is whether my skin will keep getting better or if it will just reach a point where it can't improve any more.