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Intermuscular Glutathione injections? This is the correct effective administration route?

8 replies5 peopleNov 1, 2026☆ Follow
Summary

Is intramuscular injection an effective administration route for glutathione and what are users' experiences with different injection sites and needles?

Users report trying 200 mg glutathione shots in the glutes with no post-injection pain and settling on IM to avoid site reactions. Thigh injections were more painful for some while glutes were tolerable with a full 1 inch needle. Vitamin C loading was done alongside starting one week prior. Videos were referenced for technique but specific links and brands were shared.

What this discussion establishesWhere people disagree

Whether a seated injection video shows true IM or actually subq technique

Nothing here is advice.

8 replies · 5 people
SteadyMeadow42archiveopening postNov 1

I got my kit and tried my first 200 mg shot in the glutes. No post injection pain so that's fine. Thanks to the person who helped. Anyone else using glutathione via intramuscular shots, what do you think about it?

SharpCinder28archiveNov 1

Because of injection site reactions I went with intramuscular instead. I followed some youtube videos for the vastus lateralis muscle in the thigh. Used a 27G 1 inch needle. The issue with glutes includes the chance of hitting the sciatic nerve as well as an artery.

NorthWillow72archiveNov 1

I also took a loading dose of vitamin C with 1000mg ascorbic acid powder in the morning and then 1100 liposomal vitamin C later in the day. I began that loading one week prior to starting the cycle

SharpCinder28archiveNov 1

What needle size did you use for the ventrogluteal site?

SteadyMeadow42archiveNov 1

25 gauge one inch. Those are my usual needles for AAS.

NorthFenwick56archiveNov 1

So in the second video about injecting test while seated with a very short needle it seems like subq instead of im right?

SteadyMeadow42archiveNov 1

The video starts by saying it's an intramuscular injection. I use 1 inch needles for that spot. All the videos are on that site under favorite youtube injection videos.

ClearQuill84archiveNov 1

I do gluta intramuscular using a 25g 1 inch needle. At first I injected into my thighs but it hurt like a bee sting depending on how deep. I couldn't insert the full inch because it stung too much. Glutes work better. The whole needle goes in the butt and the sting is only slight. I reconstituted a vial with 6ml of solution. For the next one I plan to use 8ml which might reduce the pain and let me go back to thigh injections.

SteadyMeadow42archiveNov 1

These are videos that I looked at.

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