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Period interfering with tirzepatide results

9 replies10 peopleOct 31, 2026☆ Follow
Summary

Can your period reduce the appetite-suppressing effects of tirzepatide?

Users report that during menstruation, tirzepatide's effects on food noise weaken, leading to increased eating and temporary weight stalls or gains of 3-5 pounds. This is followed by a 'whoosh' where weight drops suddenly after the cycle ends. Many experience similar patterns regardless of dose increases.

What this discussion establishes

Nothing here is advice.

9 replies · 10 people
LevelTimber63archiveopening postOct 31

I stayed on 7.5 mg of tirz for a full month before bumping it up five days prior to my period. Even after going up, the 7.5 dose seemed stronger than the 10. Is it possible my period is overpowering the appetite control? I've been eating way more this week compared to before. Same vial though.

SharpCinder28archiveOct 31

Found a somewhat related post sharing advice from AI.

GreyLantern71archiveOct 31

It might require several doses before noticing the higher amount working. No need to be hard on yourself. Most people seem to lose control during their cycle.

KeenThistle22archiveOct 31

Keto-carnivore approach.

GreyFenwick31archiveOct 31

My daughter mentioned gaining five pounds around her period, which vanishes two days later. The bloating is definitely noticeable. Everything should settle back to normal.

CopperQuill49archiveOct 31

A number of us experience a stall or even weight gain during that time of the month, followed by a sudden drop of about four pounds overnight once it's over.

SlowSignal37archiveOct 31

During each cycle I tend to stall or put on three to five pounds. It usually drops off by the following week. Appetite signals also get stronger.

PlainCompass54archiveNov 1

I notice a small weight increase and stronger hunger pangs while on my cycle as well.

RustSignal28archiveNov 1

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SlowLedger99archiveNov 1

Tracking your cycle alongside the scale readings makes a big difference. After you notice that same increase showing up every month it no longer feels like the tirz has stopped working.

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