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Question about stacking and syringes

9 replies6 peopleAug 24, 2025☆ Follow
Summary

Can multiple peptides be drawn into one syringe for a single subcutaneous shot, and are 31-gauge insulin syringes suitable?

Participants agree that combining the three peptides into a single vial first avoids multiple punctures and keeps the needle sharp. Most find 31-gauge needles slow to draw and prone to bending, preferring 29-gauge instead unless a medical reason exists. Reconstituting each vial separately then transferring liquids is the recommended sequence, and sterile empty vials from unverified sources raise concerns.

What this discussion establishesWhere people disagree

Whether 31-gauge or 29-gauge needles are preferable for routine use

Still open

Best vial size and source for sterile mixing containers

Nothing here is advice.

9 replies · 6 people
WryWillow28archiveopening postAug 24, 2025

I'm getting ready to start injections and want to avoid mistakes with needle choice. Research shows varying suggestions. I have a kit with three peptides at 10 mg, 10 mg, and 50 mg. The idea is to pull all three into one syringe for a shot under the skin near the shoulder. Would 31-gauge, 1 ml, 5/16 inch insulin syringes work for that?

WrySparrow78archiveAug 24, 2025
↳ replying to @WryWillow28 (opening post)

That’s the size I saw recommended just recently.

SlowLantern99archiveAug 24, 2025

In my view 31-gauge syringes are a poor choice. They take a long time to fill and deliver, some liquids make it worse, and they bend too easily. Math posted earlier showed the actual diameter difference is tiny, so without a specific medical need most users won't notice any benefit and should just pick 29-gauge instead.

QuietSignal25archiveAug 24, 2025
↳ replying to @SlowLantern99

Yes, thanks. I've run into the same slow draw and bending problems with 31-gauge needles, and keeping them straight gets harder when doing several small injections at different spots.

WarmAlder92archiveAug 24, 2025

Yes, if the ratios won't change later then mixing once and drawing once per day is simpler, cleaner, and less uncomfortable because the needle stays sharper. If responses to one of the peptides are unknown, adding a bit of another compound might be worth considering.

WryWillow28archiveAug 24, 2025

Is it better to combine them after each one is reconstituted, or to put the dry powders together in one vial first and then reconstitute? Are the sterile 10 ml vials sold online worth getting, or is there a better choice, and would 10 ml hold enough liquid for the three vials?

WarmAlder92archiveAug 24, 2025
↳ replying to @WryWillow28

Generally only move liquid out of a vial with a syringe since that is what they are designed for. More reading on the topic would help. One calculator page and its parent site might be useful, though knowing how the numbers were derived would be good.

WrySparrow78archiveAug 25, 2025
↳ replying to @WryWillow28

I hope the vials still have negative pressure inside. Leave the caps on unless the vials are empty and you need a spot for tiny amounts of sand. Reconstitute first, then combine. The best approach is to do the blending while filtering into sterile empty vials.

CopperWillow54archiveAug 25, 2025
↳ replying to @WryWillow28 (opening post)

By the time the needle reaches skin it will already be dull and possibly bent. There are also three chances for cross-contamination. Mixing everything in one vial is better. No need to reconstitute each one separately and then combine; just move the liquid from the first into the second, then into the third until everything is in a single vial. That's only my opinion though.

WrySparrow78archiveAug 25, 2025
↳ replying to @CopperWillow54

Picasso! I like it! Solid advice though.

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Question about stacking and syringes · ZyraTrack Community