CopperSignal27

That's the worry. A rodent study gave semaglutide in on-off cycles on a high-fat diet and the animals regained weight during off periods, t…

I was assuming the 400 pounds was more recent than 2016 so the effect is probably less than if it had been last year. Maybe 330 is a more r…

It depends on weight history. If someone has been overweight long term, treating it as a short fix usually fails because weight tends to re…

It seems there's a complication worth noting even if I'd rather not mention it, since the initial mass ought to be taken from before any re…

It would be interesting to locate some study that backs the claim of eating extra calories leading to greater fat reduction. That notion se…

It sounds like you respond very well to semaglutide, so I wouldn't worry too much about switching. It hasn't been studied directly, but peo…

Thanks for that. It's something I've been curious about but my own research didn't go that far. The patent info is pretty convincing that d…

I lost 70 kg three years ago. Two years ago I started semaglutide but had many side-effects even at low doses for a year, then switched to …

Blood concentrations reach their highest point about a day after each injection, meaning the lowest amounts appear right before the followi…

No one has directly measured energy expenditure in humans taking reta, so all the usual claims are estimates or taken from animal work wher…

I checked all the reference links thoroughly but couldn't find any source for the 25-30 mg doses mentioned. The only mention came from a bl…

Tirzepatide appears to have the lowest overall side-effect rates, then retatrutide, then semaglutide when all are taken to their highest do…

My negative view of semaglutide comes from personal experience plus the fact that it produces less weight loss than tirz or reta, which are…

More or less. Only a small percentage of people lose little or nothing on these drugs, so that outcome is uncommon. Stopping and restarting…

It seems like the small amounts are working for you. Based on discussions here, non-overweight individuals using reta appear more prone to …

I do not see height or age listed which would help. Assuming side effects are manageable I would increase aiming for 15 mg a week if tolera…

It's far too soon to consider switching. Retatrutide is currently the strongest option available for obesity, so if you're starting it you …

I would recommend not stacking anything. Try any peptides or supplements one at a time with a fair gap between each new addition. Starting …

After four weeks the most you would be taking is the two-milligram starting level. Plenty of people show no response at that amount, and it…

High uric acid causes two problems: gout and gradual organ damage. It raises cardiovascular risk independently, so leaving it untreated inc…