CopperSignal27
archive participant · first seen Aug 28, 2025 · last active 2d
2topics
856replies
0likes
0same experience
0best answers
replied
Reta Titration
With only about 15 pounds to lose and body fat near 20 percent, staying conservative makes sense. For people who are not significantly over…
Jul 24
replied
What to add?
I'm attempting to clarify for the thread starter the reason behind those unhelpful replies. Lacking the personal details I asked for previo…
Jul 23
replied
Roche's new GLP-1, Enicepatide.
Very similar to tirzepatide in many respects except it is a biased agonist toward cAMP at both GLP-1 and GIP, while tirzepatide is biased o…
Jul 23
replied
Those combining Reta and Tirz
I have been on 15 mg tirz and 6 mg reta for about a year and recently added 0.5 mg cagri. This is for lifelong severe obesity that is now i…
Jul 22
replied
Reta Titration
Half a milligram is quite cautious. Some here have had rough starts even at the 2 mg level the company suggests. How fast you move depends …
Jul 22
replied
Is 4lbs in 2 months not good?
Of all the GLP medications I have tried only semaglutide produced that general low-grade unwell feeling, similar to a mild virus. I do not …
Jul 22
replied
Does anyone know why reta looks less effective for weight loss in this research paper?
Without rereading the whole thing, I'm pretty sure they didn't pull in the newest reta results that showed 29 percent loss at 12 mg over 72…
Jul 22
replied
Does anyone else have this weird experience?
I've noticed that using bigger amounts together with extra versions of these meds cuts down on my appetite and stops me from wanting to con…
Jul 22
replied
Anhedonia from retatrutide doses and options for mood recovery with tirzepatide or TRT
It is interesting that tesofensine helped your anhedonia. It has not been studied in humans as an antidepressant but chemically it acts lik…
Jul 22
replied
What's your favorite workout/running shoes?
I mainly walked to improve my fitness level, and that approach succeeded for me. At my starting weight of 115 kilograms, even brief strolls…
Jul 21
replied
Does anyone else have this weird experience?
Before those treatments I would get hit with overwhelming cravings soon after tasting just a little of the richer or faster-digesting items…
Jul 21
replied
Eczema onset from Reta
It will be difficult to confirm any link to the compound because skin rashes occur often for many reasons. Allergic-type reactions to these…
Jul 21
replied
Total Cholesterol Normal but Triglycerides high?
Are you carrying extra weight? Starting reta two months ago suggests you had weight to lose. The starting A1C was mildly elevated and the t…
Jul 21
replied
Having surgery? You may not have to stop GLP1 before.
In practice the decision comes down to what the surgeon or anesthesiologist prefers so the team feels the case can proceed safely. Multiple…
Jul 21
replied
Looking for weight loss brakes!!
The amount of food you describe is lower than what most expect for weight maintenance yet after years of big losses the calories needed to …
Jul 20
replied
Non-Scale Victories on GLP-1 Journeys
I can now buy size S clothes, after beginning at 7XL where even those were sometimes too snug and bigger options weren't available in store…
Jul 20
replied
What to add?
Without knowing your present body mass, stature, desired mass, reta dosage, plus the period of usage so far, any reply stays pure speculati…
Jul 20
replied
Constantly feeling cold on Reta - is it a side effect?
Weight loss or extended low calories can make you more sensitive to cold once metabolism slows and insulation drops, but five weeks seems t…
Jul 20
replied
Thoughts on too many peps?
HGH and secretagogues like tesamorelin have complicated effects, many not well studied long term in humans. The goal is usually less viscer…
Jul 19
replied
How long have you taken Reta without a break?
I view it as a very long-term, probably permanent treatment unless someone wasn't obese to begin with. Fewer long-term studies exist for re…
Jul 19