KeenPebble33
archive participant · first seen Mar 31, 2026 · last active Jul 31
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Glutathione supplementation and cancer concerns
That is not quite right. The issue is not about spiking levels, and NAC supplies cysteine just as readily. The paper itself notes that NAC …
May 7
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Best stack for athletic performance? Reta + what?
Ephedrine gives a nice stim effect but taxes the heart. I'd skip clen, it isn't as effective and hits the heart harder. Cardarine is anothe…
May 6
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💡A 🆒🆕 Topic: ♟️Nootropics ♟️💡
Not an agonist, more of a modulator. It lowers the activity of dopamine neurons in the reward system, which leads to reduced impulsivity.
May 3
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Best weight loss peps that are not GLPs?
You seem like the perfect person for this new substance once it shows up through unofficial channels. The stuff matches glp1 agonists when …
May 3
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Anyone Switch From Reta to Tirz?
For me the sides are basically gone. The only real downside is a small extra cost over Reta. Appetite control and weight loss have been exc…
May 2
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Informed Decision
The topic needs a careful start. Pointing out that lasting weight reduction improves lifespan and lowers heart and brain risks more than ca…
May 2
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Anyone Switch From Reta to Tirz?
I went through this change. I began on Tirz and the hunger control was solid with steady weight drop. I tracked daily weight, waist size, e…
May 2
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Eloralintide (LY3841136) discussion from discovery to potential use
I would pay extra for it. I am nearing maintenance and an amylin agonist with minimal sides looks like a solid way to taper GLP-1 doses. So…
May 1
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Stopping and Restarting Certain GLP-1s to Lose Weight May Make the Drug Less Effective
These medications are gaining attention in longevity circles for heart benefits and lower mortality risk. More people at normal weight are …
Apr 30
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Stopping and Restarting Certain GLP-1s to Lose Weight May Make the Drug Less Effective
Thanks for sharing that study. It matches what I went through. The steep rebound after week 176 is especially striking and is one reason I …
Apr 30
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Eli Lilly phase 3 Eloralintide trial is enrolling for Plateau Busting research
That is a super interesting study. There is synergy between cagri and sema so I will be interested in the synergy of elora with tirz since …
Apr 29
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Stopping and Restarting Certain GLP-1s to Lose Weight May Make the Drug Less Effective
I have no faith in the reset idea. My results show clearly that it does not happen. It is also very frustrating to lose months of progress …
Apr 29
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New quintuple agonist from Eli Lilly! So new it is not yet named.
I see your point. There's a chiral center in those meds that mass spectrometry can't pick up, as you said. That means we could be receiving…
Apr 29
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New quintuple agonist from Eli Lilly! So new it is not yet named.
The whole idea of hitting five receptors at once feels like mostly hype since going after calcitonin does nothing to help drop weight and m…
Apr 29
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Stopping and Restarting Certain GLP-1s to Lose Weight May Make the Drug Less Effective
I can confirm this from my own experience. I stopped tirz for roughly two months thinking I would be fine. The weight came back fifteen pou…
Apr 29
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What do you guys think about DNP?
Like the others said I would not touch it. The safety window is very narrow with little room between helpful doses and ones that can cause …
Apr 29
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Eli Lilly phase 3 Eloralintide trial is enrolling for Plateau Busting research
Imagine what stacking it with reta or even tirz could do. Lilly is way ahead of Novo.
Apr 29
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Eli Lilly phase 3 Eloralintide trial is enrolling for Plateau Busting research
They turn out to be rather unlike each other in their makeup. The first one doesn't zero in solely on those amylin receptors numbered one a…
Apr 28
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Anyone successfully cycling SSRI?
For SAD specifically, check your vitamin D levels and consider up to five to ten thousand IU daily during winter. It may not help but tryin…
Apr 26
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Anyone successfully cycling SSRI?
Prozac is simpler to taper due to its long half-life, yet it affects libido more than some others. Lexapro differs from Prozac, Zoloft, or …
Apr 26