PlainSignal69
archive participant · first seen Oct 1, 2025 · last active May 27
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Blood Pressure Not Improving Despite Major Weight Loss on GLP-1s
Yes still taking the pressure medicines even though they seem to do little. The retatrutide dose just increased to 3 mg so it is not a high…
Dec 25, 2025
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Blood Pressure Not Improving Despite Major Weight Loss on GLP-1s
My pressure has fallen about 10 points still high but moving slowly in the right direction. The medicines my cardiologist prescribed barely…
Dec 24, 2025
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Exploring Low-Dose Naltrexone: Who Has Tried It, What For, and Your Experience?
More than four years have passed since I started LDN and I'm still using it today. My third covid episode caused awful mental fuzziness so …
Dec 23, 2025
started a topic
Cerebrolysin liquid vs powder vials and P21 comparisons for brain fog and TBI recovery
Having just wrapped up my opening round using this compound, I decided to describe how it went for me. I went with the genuine ten-millilit…
Dec 14, 2025
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Mood and Reta
My emotional state stayed completely steady across the full ten weeks I've used this.
Dec 12, 2025
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Finally pinning Tesamorelin and Ipamorelin
Dropped the tesamorelin and kept only the ipamorelin cjc blend. After research concluded the tesamorelin costs more without providing extra…
Nov 20, 2025
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Does the fatigue pass?
Had about ten days of fatigue right when I began reta. It faded over four or five days until there was none left. So it did pass for me.
Nov 15, 2025
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Wellbutrin+naltrexone
I have taken low-dose naltrexone for nearly five years to help with lingering brain fog after covid. It has helped noticeably and also prod…
Nov 4, 2025
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Food noise vs. compulsive/boredom eating
I grew up being told to finish everything on my plate and that stuck with me. By thirty I had no sense of normal portions and just kept eat…
Oct 20, 2025
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GLP-1 drugs as lifelong treatment versus tapering off
My mother was four foot eleven and over two hundred fifty pounds. My father's stomach covered his belt on three sides and he was proud of i…
Oct 19, 2025
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GLP-1 drugs as lifelong treatment versus tapering off
I grew up in the fifties and sixties and saw overweight people everywhere. Many back then viewed being heavier as healthy and thin as unhea…
Oct 19, 2025
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Does your rs heartrate keep rising with higher doses? or does it settle?
My resting rate climbed from 55 to 70 in the first two weeks on reta then eased back to 64. I haven't seen any further shift when increasin…
Oct 17, 2025
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Rapid weight loss question
A paper from NIH gives a decent overview of fasting effects on metabolism and mental health. The short version is that fasting, especially …
Oct 17, 2025
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Reta skin effects, extra sensitive to needles?
My B and D levels are both high-normal. I have them checked regularly to avoid going too high or too low. Still, I can see how low vitamin …
Oct 15, 2025
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Reta skin effects, extra sensitive to needles?
The skin sensitivity I mentioned at the two-week point disappeared by the end of week three. I used to be a redhead before my hair turned w…
Oct 14, 2025
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Finally pinning Tesamorelin and Ipamorelin
One week later and roughly ten days into the blend. The site reaction is now like a mosquito bite for about five minutes then gone. Sleep i…
Oct 12, 2025
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GLP-1 drugs as lifelong treatment versus tapering off
That matches why I also avoid calling peptides medicine or drugs. The explanation lines up with what I have been trying to express.
Oct 11, 2025
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GLP-1 drugs as lifelong treatment versus tapering off
After learning what these peptides address at the cellular level it became clear this is a long term commitment.
Oct 11, 2025
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Regret Switching from Tirzepatide to Retatrutide?
I appear more sensitive to retatrutide than most. At 1.5 mg I hit a point where I can't finish a normal-sized meal. Food ads also feel irri…
Oct 11, 2025
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Airline travel with peps possible?
Planning a journey ahead has me pondering difficulties that could occur when transporting these items along the way. Appreciate you sharing…
Oct 8, 2025