SlowLedger42

Partner and I both tried 1 mg in the afternoon. Both got strong flushing right away but no other problems. Waited hours for something to ha…

I've been thinking more about how activating GLP-1 receptors together with GIP tends to cut down on calorie consumption. That's a big simpl…

I agree with you up to a point, though maybe you were aiming for the idea of elevated average levels instead. When stuck picking between a …

Consider this hypothetical situation with a medication that has two possible dosing approaches. One option boosts patients' daily well-bein…

To be fair those doctors might not be that dumb. They could just be playing along with stubborn patients. When a month off does not suddenl…

Pharma maximizes revenue by selling all 52 weekly doses each year to every patient. A more complex schedule that causes extra sides or miss…

The argument sounds reasonable but these drugs push GLP-1 levels far above anything natural even at the low point before the next shot. The…

Weekly dosing was picked for patient compliance not because it was the best medically. Most people want a simple Friday shot day. If twice …

I'm invested in this stock so I'm not angry about it. What bothers me is how the rival's drop in value didn't boost ours right away.

Haha that physician has no clue what he is saying. He goes on about combining those hormone-like substances inside you. At the same time I …

I haven't found much either. There are lots of stories about combining survo or maz with tirzepatide, but hardly any about using either one…

Whatever choice you make, use a half-life calculator to plan the change. Dose reductions can behave counter-intuitively just like increases…

I am pretty skeptical of those studies claiming no healthy amount of alcohol. Observational data cannot really prove an absolute conclusion…

That is a good point I missed at first. The two to four beers a day could be happening during the same hours when the lightheadedness shows…

I am mostly teasing, but the body really does need time to adjust to big changes. Making two large shifts at once will challenge it more. T…

You are kind of working against your metabolism in two ways at once. Removing the usual daily carbs already requires several days to adjust…

I appreciate the detailed reply and agree with most of it, with only small differences in opinion on certain foods. I especially like how y…

One detail often overlooked is that not every restricted way of eating requires fighting hunger the whole time. Simple calorie cutting is u…

That sounds close to what I did after a diabetes diagnosis to bring weight and blood sugar under control. Mine was not low-fat but we each …

You are pointing to one trial result. That alone does not set everyday medical practice. The main professional group will wait for several …