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Peptide compatibility reports for nasal sprays and saline buffers

113 replies33 peopleJun 14, 2026☆ Follow
113 replies · 33 people · page 3 of 3
SteadyAnchor73archiveAug 6
↳ replying to @SlowThistle88

Avoid using only acetic acid because it burns badly. The method that has worked for me is to keep vacuum, bring everything to room temperature, start with a small amount of sterile water, then add BAC water to the desired dilution, check pH, and add tiny amounts of acetic acid only if needed while rolling the vial and rechecking.

GreenMeadow27archiveAug 6
↳ replying to @SlowThistle88

That approach sounds extremely painful. Please do not try it.

SteadyLedger54archiveAug 11

I bought a case of the BAC NaCl because several items on the list are cheaper that way. One of my MOTS-C vials thickened in the fridge but returned to normal once warmed to room temperature. The air bubble moves slowly when cold but the solution stays clear. I have been using it on the scheduled days with no problems during injection.

SteadyLedger54archiveAug 11

Has anyone tried Cartalax or the 5A1Q compound with BAC sodium chloride?

LevelLedger10archiveAug 11
↳ replying to @SteadyLedger54

No reports yet on Cartalax, but the 5A1Q entry came from the chloride version and showed gelling.

SharpCinder28archiveAug 12

I mixed a vial that had already been compromised using 3 mL of saline BAC. It showed bubbles and a thick gel-like appearance at first but cleared within about twenty minutes. The same kit mixed with regular BAC went perfectly with no gel phase. I would only feel comfortable trying this at lower concentrations and would not rely on any PBS buffer sold for injection use.

SteadyLedger54archiveAug 13
↳ replying to @SharpCinder28

It is the 40 mg size mixed with 2 mL BAC NaCl. It thickens when cold but stays clear and returns to normal flow after a few minutes at room temperature. Other vials from the same kit mixed with regular BAC never thickened.

RustAlder25archiveAug 14

Does the sodium chloride interfere with the copper ions in GHK-CU?

SharpCinder28archiveAug 14

A mouse study on intranasal use used plain saline without apparent immediate issues, though longer-term effects on the compound remain unknown. I have added GHK-Cu to a KPV syringe that was reconstituted with BAC saline.

SteadyAlder70archiveAug 20

The list is useful but anecdotal results should be treated cautiously because formulation differences can change outcomes. One name that came up still needs proper testing data before assuming compatibility.

SharpBeacon49archiveAug 20

After mixing NAD with BAC NaCl the solution feels thicker and harder to draw, though it stays clear and injects fine. Adding a small amount of sodium bicarb helped reduce the sting over time. Next time I may try a 50/50 mix with PBS to improve viscosity and possibly reduce the bicarb needed. I expect to freeze portions of the PBS since it comes in larger bottles.

LevelLedger10archiveAug 20
↳ replying to @SteadyAlder70

Nobody here is acting like any of this is certain. That is exactly why everything gets labeled as just reports and why the headings stay cautious. If you want real lab data then go ahead and pay for the testing yourself.

SteadySparrow75archiveAug 20
↳ replying to @LevelLedger10

Right? With zero risk tolerance I would probably stay out entirely. There might be formal studies somewhere on these topics, but the day-to-day experiences shared here are useful enough that I am comfortable sourcing and trying the compounds on my own.

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