Peptide compatibility reports for nasal sprays and saline buffers

I bought a case of the BAC NaCl because several items on the list are cheaper that way. One of my MOTS-C vials thickened in the fridge but returned to normal once warmed to room temperature. The air bubble moves slowly when cold but the solution stays clear. I have been using it on the scheduled days with no problems during injection.

Has anyone tried Cartalax or the 5A1Q compound with BAC sodium chloride?

I mixed a vial that had already been compromised using 3 mL of saline BAC. It showed bubbles and a thick gel-like appearance at first but cleared within about twenty minutes. The same kit mixed with regular BAC went perfectly with no gel phase. I would only feel comfortable trying this at lower concentrations and would not rely on any PBS buffer sold for injection use.

Does the sodium chloride interfere with the copper ions in GHK-CU?

A mouse study on intranasal use used plain saline without apparent immediate issues, though longer-term effects on the compound remain unknown. I have added GHK-Cu to a KPV syringe that was reconstituted with BAC saline.

The list is useful but anecdotal results should be treated cautiously because formulation differences can change outcomes. One name that came up still needs proper testing data before assuming compatibility.

After mixing NAD with BAC NaCl the solution feels thicker and harder to draw, though it stays clear and injects fine. Adding a small amount of sodium bicarb helped reduce the sting over time. Next time I may try a 50/50 mix with PBS to improve viscosity and possibly reduce the bicarb needed. I expect to freeze portions of the PBS since it comes in larger bottles.

Just reconstituted tesa using 3 mL of BAC saline. Nothing unusual so far. The kit was labeled 10 mg but tested at 11.2 mg. Like most other peptides, except maybe the high-milligram versions of reta, going with 3 mL keeps the concentration lower and might reduce the chance of gelling.

Reconstituted two vials of SS-31 from separate sources, one 50 mg and one 10 mg, using BAC saline. Both went crystal clear and dissolved very quickly with 2 mL each. Filtered them and put them in the fridge. Will check later how they hold up.

Did yours arrive yet? Have you tested RT using the bac saline and PBS mix?

1000 mg or 500 mg with 5 ml? I have done NAD+ at 500 mg in 3 ml BAC NaCl twice already. Reconstitution went perfectly, stayed thin, and no sting or injection site reaction at all.

So what works best as a thinner for KPV?

The tesa went back to normal once warmed, but I still consider it trash. It came out of the fridge as a very cloudy gel.

I meant to try my PTB reta but ended up adding 2 ml regular BAC first then 1 ml of the other BAC afterward on the CSX material. At least with that ratio and order there was no cloudiness even when it got quite cold. That was different from an earlier attempt with the same 10 mg CSX where the other BAC went in first and regular BAC last, which still clouded at room temperature.

Just an update that the SS-31 in the fridge has stayed clear with no gelling. I tried a shot this morning and noticed less injection site reaction than with BAC.