Splitting tirz dose and taking twice weekly.

I had to split my 7.5 mg dose into two as well. Around day four after a full shot I would get sulphur burps, diarrhea, and painful cramps that kept me home from work. Only sleep stopped the pain. After the worst 24 hours it would suddenly end. I went through it three times before I started splitting. The last time, only Pepto let me work most of the day.

It evens out the pulses. There is no clear research yet on whether the weekly peaks are helpful or if steadier levels are better. You might adjust the split amount so average levels stay close to the original weekly peak rather than matching the old peak exactly. There are online tools that let you plot levels for different schedules.

I switched to every five days because hunger came back hard on days six and seven and ruined my weight loss. Now on a different medication I do twice a week to avoid peaks and side effects, and it works well with no sides. It has not been studied in trials so nobody really knows, but plenty of people split doses anyway.

A calculator lets you enter the weekly target and injection frequency and tells you exactly how much to draw each time. I use every-five-days shots and it keeps me from going over my intended weekly total.

I am splitting to avoid hunger on days five through seven. I do 4 mg Monday night and 4 mg Friday evening. It is working pretty well. I still think about food but much less than when I injected once a week.

I inject once per day. It is hard to see what extra monitoring a doctor would add beyond weekly checks. With brand pens there can be physical difficulty splitting doses. One solid argument against more than weekly injections is that the drug was only tested on a once-weekly schedule. I think my side effects are lower and appetite control is steadier on a lower per-dose amount because I skip the valleys that come with weekly dosing of something with a five-day half-life.