Any Tesamorelin users in here.

I would personally keep it in the fridge and finish that vial within about a week.

I used it for roughly five months before moving over to growth hormone. It is supposed to hold up fine at room temperature. The clinical dose is 2 mg at bedtime.

The key is 2 mg before bed with no food for three hours. It gets expensive to keep running.

It has worked well for both my wife and me as part of our protocol for over six months. We notice better sleep, reduction in visceral fat around the midsection, and improved vascularity. We each use 2 mg every night. It is pricey though.

I have read that it does not stay stable very long, but I usually only use half a milligram daily so a 10 mg vial mixed with 2 ml of bacteriostatic water lasts me about three weeks and I have not noticed any problems. I keep mine in the fridge and have not had any turn to gel.

Keeping it in the refrigerator has been inconsistent for me. Sometimes it gels and I lose two vials, sometimes it does not, even with the same bacteriostatic water. Moving it to a dark cool spot outside the fridge has been the only reliable option so far. My view is to keep it out of the refrigerator once mixed.

I bought only one kit. I did not like the water retention so I stopped after five days and repeated that twice. I froze the second reconstituted vial. I am now on the third vial which has been in the fridge just over a week. All vials stayed clear with refrigeration. Night dosing gave me intense dreams that I kind of enjoyed but I woke at 3:30 every night. Switching to morning fasted feels great with an energy boost and mental clarity and hopefully better workout gains. I have a pen coming and plan to load two or three weeks worth into it and keep it in the fridge, though I might thaw the frozen one first to test. I prefer 1.5 mg plus 375 mcg ipamorelin in the morning with refrigeration.

Thank you everyone. I am excited and nervous at the same time.

I decided to drop the tesamorelin. My tes levels are already maxed so I figure my growth hormone is high enough. Thanks for the feedback. By the way daily fasting boosts tes and growth hormone while also lowering cholesterol and blood pressure. I have been doing it for years.

I am about to start a tesamorelin plus ipamorelin cycle and plan to pin first thing in the morning to stay fasted. The question I have not seen addressed is how long after dosing I need to stay fasted before having my morning protein shake. Is it still the recommended two-plus hours like an evening dose or does the effect finish sooner so I can eat earlier? I also plan to start at 500 mcg tesamorelin and 250 mcg ipamorelin then move to 1 mg and 0.5 mg. I do not see many people mentioning their ipamorelin amounts, only tesamorelin doses usually between 1 and 2 mg. Is a 2-to-1 ratio okay? This is a new peptide area for me.

I use tirzepatide which delays gastric emptying. I took 2 mg in the morning and stayed fasted for fifty days. I just finished two weeks ago. My blood work was comparable to growth hormone and I lost two inches off my waist. Joints got sore and carpal tunnel showed up in the last few weeks. I reconstituted and left it in a dark cabinet and used the whole kit the same way.

The branded product does not equal other versions of tesamorelin because its formulation was specific. Tesamorelin is a bit more sensitive than other peptides which is why Hospira bacteriostatic water is really needed. It is not going to become contaminated and useless after a week though. I would not go past a month but even a kit is only going to last around two weeks and that is commonly available. Reconstitute with Hospira, put it in the fridge, and pin.

Been pinning 2 mg tesamorelin and 150 mcg ipamorelin five days on and two off with good results so far.

Only recently began this routine. Picked up the mixture. Taking a dose of two over point six milligrams each morning right after waking. Still too soon to notice any changes yet, though staying optimistic.

After looking into when to take these compounds especially the newer one I reached a few takeaways. Growth factor levels follow the size of each growth hormone surge and insulin from food reduces that surge right at the source so keeping an empty stomach matters more than aligning with the body clock. Because growth factor itself stays steady for a long time and averages exposure over many hours its overall buildup happens across weeks so shifting a dose earlier creates almost no downside. The only situation where evening could still look better is if a fully empty stomach window opens up then the combined effect might tip the scale so preferring morning only holds when the later option includes food. The newer compound leaves this picture unchanged its slower stomach emptying just makes the early empty period even cleaner while better insulin response supports the surge the liver resistance tied to calorie shortage lowers growth factor regardless of clock time. One extra detail stands out though the receptor tied to growth hormone releasing hormone directly supports deep sleep through a brain area separate from any actual hormone output that action only works if the compound is still active near bedtime which a quick-clearing version needs an evening shot to achieve and the sleep link comes from the receptor itself not from downstream hormone changes as shown by how other secretagogues split the effects.

So you need to be fasted three to four hours before pinning and then a couple of hours fasting afterward too? If pinning in the morning how much gap is required before breakfast?

I am about ready to start. My tirzepatide and diet combo is not targeting visceral fat so something else is needed. I am thinking of starting at 500 mcg. Maybe 250 mcg is a better starting point? Not sure.

Before trying any of those releasing agents, checking my growth factor readings seems like a good idea to me. I went ahead and had mine checked, discovering they sat at 257 naturally, which has me questioning if that option would bring noticeable improvements.