User experiences dosing timing and effects of mitochondrial peptides SS-31 NAD+ with GLP-1 agonists

I'm wondering about the right way to keep my unreconstituted NAD+ vials. Some AI info suggests avoiding the freezer due to how fragile the molecule is. Maybe I made a mistake since I've been putting them in the freezer alongside my other peptides. It mentioned that ice crystals might cause harm. Though it did indicate that other peptides handle freezing fine. What methods do you all use for storing yours?

Just wrapped up that whole sequence with the three compounds and took the final mots-c injection. Felt good to finish. It looks like my cells needed some fixing since the whole thing made a difference for me. My times in the pool stayed the same. I got stronger but that came from lifting weights alongside the other peptides and this round just supplied extra drive so I could train longer and more often. One question is still open. I followed the schedule I had noted down. The nad produced no reaction until I reached the higher dose and then only a mild warm sensation across my upper body a few minutes later. The opening ss-31 dose came after a fourteen-hour shift and within ten minutes my head felt clearer than it had for ages while the heavy tiredness from the day eased even though I remained worn out. That was the single occasion any of those shots registered. Partway through the course I was abroad and combined the remaining nad into one dose to skip carrying it back through security. That turned out poorly and produced an uneasy surge plus chest pressure that hung around for four hours. The first pair of mots-c injections hurt and caused a raised spot that stuck around for days. After that I mixed each one with extra liquid and rubbed the spot hard afterward so the soreness and swelling stopped happening. Early in the mots-c phase my reflexes got noticeably quicker so I could grab things that slipped off surfaces the way I used to years ago. I also saw steadier recall and sharper thinking overall with words that used to stick now coming out right away. These shifts built slowly and have not left yet. Near the close of that phase I tried the nad ahead of the long shifts and had solid extra stamina that let me finish without dragging. I had wanted better strength and speed in movement but nothing showed up there. The mental gains were unexpected. I hope they hold now that everything is done and I will probably repeat the round later on. I may also use the nad ahead of those extended work periods.

Just wondering about the schedule you follow with tesamorelin and ipamorelin. What amounts do you use each time, over what period, and whether you combine the injections or do them individually?

I've been tracking updates from a doctor whose background lists certification through ABAARM covering aging prevention plus tissue repair methods, an A4M fellowship centered on lifespan extension, and separate A4M approval for peptide treatments. The same person finished one year of extra emergency medicine work at the University of Chicago after earning an MD degree there, holds CSCS status from NSCA, and studied biomedical engineering at Purdue. Their recent discussion covers an FDA-cleared mitochondrial peptide, going over its main upsides along with amounts, timing, and cycle lengths.

Quick update on my routine, I experimented with switching back to nighttime tesa while holding ipa to morning and midday slots, yet ended up stirring every hour or so once more. Now shifting to the tesa plus ipa combo right at the start of the day, plus one more ipa shot after training no later than mid afternoon. That lets me drop off right away once evening hits and only stir a couple times, right at the bottom of what I usually see. Others often mention better rest from evening shots of this mix, yet for anyone dealing with the reverse there's still another option that works. Also spotting shifts in body shape after three weeks, so it makes sense to keep going.

What dose do you take in the evening hours resulting in this kind of trouble falling asleep?

Before switching to the Tesa and Ipa combo I ran GHRP-2 with Sermorelin. The GHRP-2 also went morning and afternoon because the quick hunger hit was something I wanted to avoid near bedtime. Sermorelin stayed at night and left my sleep noticeably deeper and more restful than before any peptides, even though I still woke every two hours like clockwork. That regular pattern didn't bother me enough to change anything. Overall I will probably switch back to GHRP-2 instead of Ipamorelin later since the daytime hunger was manageable and I would rather have the stronger effects plus the better sleep. On the other side of the stack I plan to bring in CJC at some point and just keep testing different combinations, doses, and timings until I land on what suits me best.

Sorry for drifting off the mitochondria repair thread. Just to connect it back, one reason I am sorting out the Tesa and Ipa stack right now is so it can serve as a steady base when I begin my own mitochondria work next month. I want the dosing and schedule locked in ahead of time so I am not tweaking the Tesa and Ipa while adding the mitochondria peptides, which should let me track changes more clearly and credit them to the right compounds.

Have you tried pinning the Tesa at around half a milligram at night? That amount seems to hit the sweet spot for solid sleep with the Tesa and Ipa combo for me. I ran out of Ipa but from what I have seen so far the best sleep I have had in a long time came from half a milligram of Tesa plus maybe one fifty to two hundred micrograms of Ipa. Larger Tesa doses at night did not work as well for me while bigger daytime amounts helped mood and focus a lot. I am trying another growth hormone secretagogue now and it is not as effective, probably because I am underdosed. I will take a break then return to Tesa and Ipa at roughly that three to one ratio at night and one to one point five milligrams during the day. That balance seemed to give the most value from the stack. Everyone responds differently and I had Reta in the mix at the time. Mitochondrial repair sits at the center of my peptide approach and getting sleep right is one of the main pieces still missing. I did not expect Tesa to help as much as it did once I dialed it in.