Finger Numbness During Sleep and Computer Use While on Multiple Peptides

Tesamorelin and ipamorelin are the ones triggering carpal tunnel. It's a known effect that comes with HGH and anything that pushes growth-hormone release.

This happens to me pretty often even before any peptides, and it usually turns out to be a nerve getting pinched in my neck. When I get an adjustment and tell the chiropractor exactly which fingers are affected, it clears up for a while.

I think the last comment is right and this is carpal tunnel. There are treatments you can look into. I also run Tesamorelin and Ipamorelin but haven't had any problems yet.

At least it's not the pinky and the two next to it. That usually means the ulnar nerve is trapped and it's miserable. I can tell you from experience.

GLP-1 drugs are known to cause peripheral neuropathy, more often in diabetics but it happens. I'm not a doctor so this is only what I'd do myself: stop the tesa, ipa, and reta, wait for the symptoms to disappear, then reintroduce them one at a time over months to find which one is responsible.

The fact that the pinky isn't involved makes carpal tunnel the clear answer. The secretagogues are probably causing water retention that squeezes the nerve inside the wrist tunnel.

Different situation, but after I dropped a lot of weight my arm would go numb while sleeping, especially the right two fingers. Once the fat was gone, just resting on the mattress pressed on the nerve at the elbow. A padded elbow sleeve took the pressure off and eventually the problem went away on its own.

Check out ARA-290.

Since you're using peptides that raise growth hormone, and carpal tunnel is a well-known result of higher GH, you should stop or at least lower the Tesamorelin and Ipamorelin. If the numbness doesn't improve or stays constant, see a doctor because nerves can be damaged for good. Getting IGF-1 and blood-glucose checked would also be smart. It's worth reading up on side effects before running these compounds.

I'm also betting on the Tes and Ipa. Have you had recent bloodwork? I just got mine done. When you're using GH peptides you should check bloods at the start and every couple of months. What daily amounts of Tes and Ipa are you running?

I'm going to quit the tesa and ipa. This is getting too worrying.

After two days off the IPA and TESA the numbness stopped, so I'm restarting today but dropping the Tesa from 500 mcg down to 1.25 mg daily. I get 1 mg from the Tesa vial and 250 mcg from the blend, both at night. I thought these were supposed to help immunity, yet I just had a bad three-day cold that only the flu has matched before. Next winter I'll look for a peptide aimed at immune support instead.

After stopping Tesa for about a week and restarting at a low dose the carpal tunnel came back strongly. I took a double dose of the eplerenone this morning hoping it's just water. Even holding my phone to type this makes my left hand go numb. Tesa is really strong stuff.