CommunityBloodwork & Biomarkers

What kind of Labs do you

13 replies6 peopleMay 11, 2026☆ Follow
Summary

What bloodwork panels should I order to monitor my peptide or supplement stack?

Users on tirzepatide, GHK-Cu, tesamorelin and similar compounds report ordering CBC, CMP, lipids, glucose/A1C, thyroid, kidney/liver panels every six months. When GH peptides are involved they add IGF-1 and sometimes estradiol, progesterone, cortisol or hs-CRP. Several people stress getting baseline labs before changes and watching trends rather than single snapshots. One user saw IGF-1 rise from 165 to 401 on tesamorelin before lowering the dose.

What this discussion establishesWhere people disagree

Whether a physician order is required or whether direct-to-lab services are preferable

Still open

How often to retest IGF-1 after dose adjustments and what exact additional panels are worth adding for general health

Nothing here is advice.

13 replies · 6 people
WarmQuill56archiveopening postMay 11

What bloodwork are you running to keep track of your stack? I just had some labs done for testosterone, estrogen and a few other things. What compounds are you using and which tests do you think matter most with that protocol?

PatientMeadow74archiveMay 13

I'm on 7.5 mg of Tirz each week plus 1.5 mg of GHK-CU daily along with some vitamins. Nothing too extreme. Every six months I get the usual set: CBC, glucose, insulin, A1C, thyroid panel, liver panel and kidney panel. My A1C has dropped 1.5 percent and thyroid numbers are moving in the right direction. I'm thinking about adding estradiol, progesterone and cortisol next time but haven't done it yet.

GreenQuill96archiveMay 13

I finally placed a big order for labs. Basics plus prostate markers, testosterone, IGF-1, nutrients, minerals, electrolytes, progesterone, prolactin, hs-CRP and several thyroid tests along with kidney function. There were even more but I can't recall them all. They drew a lot of vials and I have to return in a couple days for the rest. The tech asked some odd questions since I didn't go through a doctor. It felt like she thought something was off.

PlainWillow50archiveMay 13

It depends on what I'm taking, but I focus on tracking how each thing actually works instead of copying random protocols. The core ones I watch are CBC, CMP, lipid panel, fasting glucose and A1C, total and free testosterone, sensitive estradiol, SHBG, IGF-1 when on GH secretagogues, occasional thyroid panel and CRP for inflammation. With GLP-1s or GH peptides, baselines matter more than online debates. I care more about trends over time than hitting influencer ranges. Best to test before anything starts, then again after each change rather than adding five things at once.

WarmQuill56archiveMay 13
↳ replying to @PlainWillow50

With IGF-1, what shifts have you noticed before and after your protocol? What exactly are you running for the GH peptides? I'm ordering more tests on my own without a doctor. I already have CBC, CMP, A1C, testosterone, SHBG and free T from recently. Appreciate the details.

PatientMeadow74archiveMay 13
↳ replying to @GreenQuill96

Techs have made a few casual remarks about the volume of blood, mostly just to chat. I've never tried ordering without a doctor's request. My doctor is pretty open and will approve almost anything I ask for. She usually says it can't hurt.

PlainWillow50archiveMay 13
↳ replying to @WarmQuill56

I used tesamorelin alone without ipamorelin. Started at 1 mg daily, moved to 1.5 mg after a month, then 2 mg around week ten or eleven. IGF-1 was 165 with z-score 0.1 on January 15. By March 16 it reached 401 with z-score 2.5. I dropped straight back to 1 mg daily a few hours after dinner and plan to recheck in June.

GreenQuill96archiveMay 14
↳ replying to @PatientMeadow74

Not having the doctor order made it awkward. I felt I should have spoken up more because the draw is just a snapshot anyway. They only did half the tests and want me back Monday for the rest. At most it's 270 mL, less than a donation. I wonder if I should ask for everything at once or a discount on what they already took. This is my first time handling bloodwork this way.

CopperMeadow64archiveMay 14
↳ replying to @GreenQuill96

These days you can order labs directly without a physician. It's straightforward and inexpensive if you pick the right service. I run them every ten to twelve weeks.

LevelThistle44archiveMay 14
↳ replying to @GreenQuill96

Why split the draws? Did you pay for everything upfront or in two parts? With my membership the draw and order fees are covered. I've gone back for extra tests after an initial draw and once had forty panels done with thirteen vials, no issues.

GreenQuill96archiveMay 14
↳ replying to @CopperMeadow64

I used the same lab service and went to the usual draw site. I ordered a package plus extras. The invoice listed hormone and endocrine tests including ACTH, cortisol, DHT, estradiol, IGF-1, a men's panel, progesterone, prolactin, PSA, several thyroid markers, plus metabolic, cardiovascular, liver, kidney, inflammation and hematology panels. Also enzymes like amylase, lipase and CK.

CopperMeadow64archiveMay 14
↳ replying to @GreenQuill96

That sounds like the full "what's wrong with me" set. The real value comes from repeating the same markers to see trends. One-off numbers rarely tell you much.

GreenQuill96archiveMay 14
↳ replying to @CopperMeadow64

I began with the basics plus IGF-1 and testosterone. Then at forty I started worrying about prostate and thyroid, plus what the extra weight had done to my liver before I lost it. The list grew quickly from there.

WarmQuill56archiveMay 14
↳ replying to @GreenQuill96

That's a solid price. You can feed the results into an AI tool to help interpret them. I'd be fine paying that amount twice a year on top of my regular yearly check.

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