Weight Gain, and new plan. Looking for ideas and stories.

I reached the top levels for both at different times, though not for very long stretches.

I hike four miles three or four times a week plus some light lifting. Eating is solid during the week but looser on weekends because of plans. The meds helped a lot with appetite early on but now it's just normal. I've heard the diet and training talk plenty of times and nothing else has matched what these meds do. Still, my real questions are whether going past 15 mg on the first one helps and whether tiny amounts of the second one add anything useful.

Fair enough. Those basic checks are like tech support asking if you rebooted.

Weekly average deficit matters more than day-to-day. Aim for about 3500 below maintenance per week to drop a pound. These meds can be overridden if you keep eating anyway. Higher doses of the first one have shown some extra effect in trials up to 25 mg, though returns diminish. Adding a bit of the second one brings in the third receptor pathway that increases energy burn and fat breakdown.

What day do you inject? Shifting to Thursday might line up better appetite control with the weekend when plans tend to happen.

Good idea. I picked Wednesday on purpose so days six and seven fall on Monday and Tuesday.

The flat feeling is genuinely rough and gave me more understanding for people dealing with actual depression. I couldn't handle it long term. It hit both times I tried the second med and seems to start above 6 mg weekly for me, so I'm hoping a small blend keeps it away. My diet and training aren't perfect either, which is why I'm still looking at these options.

I saw that thread before joining. Not really worried about safety with the first med since it has agreed with me so far, aside from some tiredness the next day. Sixty milligrams a week is quite a run though.

Do you take the 3 mg of the second every seven days?

Yes, 3 mg of the second every Thursday morning.