CommunityDosing & Titration

CJC no dac + Ipamorelin ratios and dosage

15 replies11 peopleMay 17, 2026☆ Follow
Summary

What dosing ratios, schedules, and results do people report with CJC-1295 no DAC plus Ipamorelin?

Users describe personal protocols ranging from single bedtime injections to split morning and night doses, mostly at 1:1 ratios between 100-250 mcg each. Several note improved sleep and body composition changes after a couple weeks, while one person measured an IGF-1 rise to 405 on 250/250 mcg twice daily before switching to HGH. Fasted timing is repeatedly emphasized for any effect, and a few prefer morning dosing due to digestion or sleep interference.

What this discussion establishesWhere people disagree

Whether morning or evening administration produces better overall results, and whether the peptide blend is worth continuing versus switching to HGH for convenience and safety data.

Still open

Long-term optimal dose, how much the observed body-composition changes are truly from the peptides versus other factors, and individual response variability.

Nothing here is advice.

15 replies · 11 people
ClearMeadow76archiveopening postMay 17

Hi folks, I'm wondering about the ways folks handle amounts of that combo blend. Some methods divide the intake into early and late parts of the day, while others adjust the mix to equal parts or favoring one over the other. Anybody care to mention their usual day-to-day intake patterns along with those mixes, plus whether dividing changes the effects?

WarmThistle43archiveMay 17

I've acquired the mixture and taken a single serving each night ahead of sleep. Curious too about the various proportions others are trying.

AmberMeadow80archiveMay 17

Searching around for the right amounts to take and what effects follow has been my focus lately. I'm not entirely sure I've found the best approach yet and keep seeking additional details. Began using one hundred micrograms of both compounds prior to sleeping. At first it was immediately before lying down yet through experimenting I found that half an hour beforehand works better for me. Sleep has been excellent on numerous evenings though poor whenever alcohol was involved. From now on I'll avoid the injections on days with a few drinks. On the seventh morning I added one hundred micrograms of each right after waking. I hope the claims about reducing fat aren't just stories. I'll keep the evening administration as well. On the ninth day I increased to one hundred fifty micrograms for the two times daily. I'll keep posting updates.

SharpTimber40archiveMay 17

Timing works either way provided several hours have passed since the last meal. Mornings suit me better since bedtime follows eating pretty closely. Some sources suggest evening hours if the goal is extra effects or rest advantages. Equal parts at 125 micrograms each is my usual amount. After missing one session I bump it to roughly 175 apiece. That pattern has suited me fine so far. The head rush still feels new though.

GreenHarbour31archiveMay 18

Earlier I described doing two daily doses of 250 micrograms each, which raised my IGF-1 to 405, a level I consider suitable for ongoing use. Switching to 4 units of growth hormone daily produces the identical reading. Individual results differ. I'm choosing to continue with the growth hormone due to needing only a single daily injection, along with greater information on extended safety and reduced chance of histamine issues. Despite notable initial reactions, I personally feel much improved while using it.

ClearMeadow76archiveMay 19
↳ replying to @GreenHarbour31

Appreciate the response it really clarifies things. Were you beginning with smaller amounts before gradually increasing? What benefit stood out most from the results with that combination? Also curious how the growth hormone has been going lately since I might switch over to it soon myself.

WarmAlder51archiveMay 19

I consume this roughly a quarter hour prior to sleeping since that's when the biggest natural growth hormone surge occurs and these enhance it. At that time I'm typically without food for around three hours. I found out that using it without being in that state was basically equivalent to discarding it. By without food I refer to no items containing energy. For the amount I've mixed mine up to total three hundred milligrams meaning one hundred fifty for each component.

CopperMarble29archiveMay 19
↳ replying to @ClearMeadow76

I find that human growth hormone works better overall. It produces a bigger and more prolonged pulse of growth hormone, helps release fat stores more efficiently, and makes it simpler to trigger extra cell development. Also, shots are needed much less often. When growth hormone is injected under the skin from an outside source, the levels stay up for around six hours, mainly from how slowly the liquid absorbs through the fat tissue. In my own case, after using a mix of two peptides for some period, where one is notably more powerful than the other, my IGF-1 went up fifty percent from one hundred ten to one hundred sixty, and my z-score moved from negative point zero five to point five times the upper limit. Reports from others indicate some respond very strongly, reaching two or three times their normal amounts. Daily use of four international units of growth hormone gets my IGF-1 to about four hundred with one point seven five times the upper normal. Research into a different peptide with a longer duration showed it could boost growth hormone by two to ten times and IGF-1 by one and a half to three times over nine to eleven days in healthy people.

CopperBeacon88archiveMay 19

I take the combination right after waking up on an empty stomach and notice warmth spreading through me almost right away. Using it later in the day never gave me that same rush. It might be because I hadn't gone long enough without food by bedtime or perhaps the other substance plays a role. Someone mentioned trying these peptides earlier instead of later since the glp agonist slows gut movement so true fasting is tougher at night. Not sure if that's accurate but the effect showed up clearly for me in the morning.

ClearMeadow76archiveMay 19
↳ replying to @CopperMarble29

Understood, perhaps growth hormone will be my next option after a couple months on the current peptides. I'll dose 300mcg divided between morning and evening on an empty stomach and may adjust higher to 400 or 500 depending on my response. I'll check out the writeup to see whether it reinforces my plan, thanks a ton.

AmberMeadow80archiveMay 26

I've completed three weeks with this particular regimen. Dosing at one hundred fifty micrograms each evening, approximately two hours following my final meal. Another dose of the same amount occurs upon waking, with breakfast delayed by three to four hours. Nighttime rest has gotten steadily better. Although sleep was already solid, I now drift off more quickly and remain asleep for most of the night. Additionally, I've used a different substance for two and a half months. Weight reduction was one and a half to two pounds per week before starting this, but only about two pounds over the recent three weeks. My fitness tracker however reports gains in muscle and losses in fat. Body fat is visibly lower as well. For the first time recently, I'm not worried about my appearance without a shirt. I had doubts initially about the results this would deliver, yet I've been impressed by the outcomes. The intention is to keep going another five weeks, reaching eight in total.

KeenKettle50archiveMay 26

250mcg each every night. It gives me a warm fuzzines.

LevelThistle44archiveMay 26
↳ replying to @AmberMeadow80

Can that gadget on your wrist check what your body is made of?

PatientLedger69archiveMay 26

I take my shots first thing each day before any food. Early on I tried them right before lying down but that threw off my rest at night. From what I gathered this compound slows how food processes so more time needs to pass after eating. Heading to bed without anything in my stomach never appealed to me. Daytime timing fits my schedule better and after a month of it I notice solid daily drive plus my lifting numbers stay steady.

AmberMeadow80archiveMay 26

The readings vary quite a bit when checked each day yet the general patterns become visible across wider periods.

AmberMeadow80archiveMay 26
↳ replying to @LevelThistle44

That's right. My watch tracks body stats with bioelectrical impedance the way certain scales operate. The earlier post includes some of those readings. The replies got mixed up while I juggled a laptop and phone together to upload the device images.

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