CommunityBloodwork & Biomarkers

Blood work

14 replies9 peopleJan 14, 2026☆ Follow
Summary

Should I get bloodwork before starting tirzepatide and what markers matter, especially if using grey market sources?

Participants generally support getting baseline bloodwork before beginning tirzepatide even without a prescription. Common suggestions include CBC, thyroid panel, A1C, glucose, lipids, and vitamins. Several users obtained labs without disclosing use to their doctor and value the data for tracking changes over time. Some rely on prior results while others prefer fresh tests to monitor specific improvements.

What this discussion establishesStill open

Whether labs must be completed before the first dose or can be done shortly after starting

Nothing here is advice.

14 replies · 9 people
KeenFenwick16archiveopening postJan 14

I'm curious whether basic blood tests make sense before beginning tirz and, if so, which markers would be most useful to check.

BlueBramble59archiveJan 14

My physician ran the standard CBC panel along with thyroid tests as the starting point. They also suggested checking B and D vitamin levels since deficiencies are common and straightforward to address. I added hormone levels for a personal baseline and found the results informative.

PlainKettle41archiveJan 14

Checking things out is worthwhile even without any new compound. Ask for whatever your doctor will approve including glucose, A1C, testosterone, lipids and vitamins. A body composition scan beforehand can also help track trends over time.

LevelPebble75archiveJan 14

Bloodwork is always sensible.

KeenFenwick16archiveJan 15

For those already using it, does your doctor know? Mine is unaware because I'm sourcing it myself and prefer not to mention it.

CopperTimber28archiveJan 15

I asked my naturopath for bloodwork but didn't mention what I'm taking. I simply said I had lost weight and wanted current numbers.

LevelThistle44archiveJan 15

I've had quite a bit of testing done, partly to rule out problems and mainly to create a starting point so I can follow changes throughout the process.

IronThistle42archiveJan 15
↳ replying to @KeenFenwick16 (opening post)

A1C is a solid and routine baseline marker worth including.

QuietTimber26archiveJan 15

I went a long stretch without routine testing. When I started on compounded product some labs were ordered but none since. A basic CBC and chemistry panel would cover the main areas like thyroid and A1C.

KeenFenwick16archiveJan 15

I already have labs from last year and nothing major has changed for me, so I'm wondering if I can skip new ones. If I do get them, does it matter much whether I start this week and test soon after or wait until the labs are done first?

IronThistle42archiveJan 15
↳ replying to @KeenFenwick16

If cholesterol or heart concerns are on your mind, a lipid panel before starting and again after a couple months can show the effect. The same applies to A1C for tracking diabetes risk.

KeenFenwick16archiveJan 15
↳ replying to @IronThistle42

That's why I considered using the older results. My cholesterol was elevated and A1C was borderline, so they might still give a sense of progress, though a year is a long gap.

IronThistle42archiveJan 15
↳ replying to @KeenFenwick16

Self-pay labs from major providers are straightforward to order and results arrive quickly. I recently paid a modest amount for the two tests I wanted.

LevelThistle44archiveJan 15

Whether to do bloodwork is a personal choice when self-managing. I prefer having data points because I'm focused on measurable improvement and plan to use standard lab services for reliability.

GreyPebble84archiveJan 15
↳ replying to @IronThistle42

I agree completely. Testing every three months works well for my situation and has given me clearer health insights than waiting on insurance schedules.

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