Users report trying 100-300 mcg doses either at bedtime or morning while fasted, with some noting better recovery and sleep but others seeing no benefit without strict fasting. Allergic reactions and injection-site issues appeared for a few after weeks of use. Several switched to actual HGH after finding the peptides less effective. Morning dosing helped one user maintain strength while on a GLP-1.
What this discussion establishesWhether bedtime or morning dosing is preferable, and whether the peptides are worth continuing versus moving to HGH
Still openLong-term safety and ideal dose for older users
Nothing here is advice.
Got CJC plus I coming in. Dosing advice conflicts quite a bit. Some say take it before bed while fasted, others say first thing in the morning while fasted. Amounts range from 100 mcg up to 1 g. Would like to hear from guys around my age since I am 50.
Been running it a couple months now. I dose sometimes in the morning and sometimes in the evening depending on when I can stay fasted. Using 300 mcg and it seems to help recovery more than anything else. I am 67 and lift three days a week.
First dose gave me strong side effects, which at least confirmed it was real. After that first time the sides went away and it has been improving my sleep when I take it before bed on an empty stomach.
Running 250 mcg of each before bed Sunday through Thursday. The idea is that the biggest natural GH pulses happen right after falling asleep so the shot lines up with that. Hard to stay fasted that late though. I am 44.
This combo can trigger allergic reactions and injection site problems. Started at 100 mcg and never needed to go higher. More is not necessarily better because there is a ceiling on how much growth hormone the body will release. Watch for full-body itchiness or hives as a warning sign. Looking into an epi-pen because some people handle it fine for a while then suddenly do not.
Without fasting the shot does nothing. Ran it six months then switched to hgh and that was the better move with no comparison between them.
Smart move. I had a severe allergic reaction after using it for a couple months and it really scared me.
Heard the same thing about Mots-c. How hard is it to get an epi pen anyway.
Will give it a try then move to HGH for sure.
If you are also on a GLP-1 then bedtime dosing is pointless because you will not be fasted. Any insulin blunts the effect and the slowed gastric emptying makes staying fasted nearly impossible on a normal schedule. Switched to weekday mornings at 250 mcg each after realizing the mistake. Training days became easier with less joint pain and steadier strength once I made the change. All anecdotal with no bloodwork to back it up.
Would you share more about what happened? Did you get any injection site reactions ahead of time or any other signs that tolerance was dropping?
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