Fatigue?

I've mostly noticed it in women for some reason, usually a day or two after the shot.

It hit me hard the first two months, sometimes feeling like narcolepsy. Once my body adjusted it mostly went away. Now it only shows up if I skimp on protein.

On a low dose I actually feel more energetic, especially during workouts. My partner started and has more fatigue, though that might be the kids more than the medication.

For me it's mostly low motivation even though I can still sleep. When it hits, work and training both suffer.

Yes, I raised the dose too fast and felt quite tired the first week. Dropping back down made the fatigue much milder.

No fatigue for me or my wife. We both began at 2 mg and are now at 5 mg twice a week. We've also used SS-31, MOTS-C, and NAD+ a few times weekly.

I'm actually feeling good energy on Reta right now. Adding Semax a week ago seemed to lift it further. It probably depends on the person. I'm only slightly overweight, which might be why my response is positive.

Not really. I'm tired by the end of the day and sleep isn't great, but I manage. Some days are better. I get up around 5 and go to bed around 8. It was worse a month ago until I started using Liquid IV in two Gatorade bottles, one a day. That helped, though I watch the sodium and only use half a packet.

I had some fatigue at the start, but then realized I was barely eating or drinking when work got busy. Once I increased calories and paid attention to water, energy improved and sleep got better too. Tiredness seems tied to the deficit, but the same deficit feels easier on Reta than off it.

Started eight weeks ago. Some fatigue showed up in weeks three and four the day after pinning, but it wasn't major. Now the only tiredness comes from the calorie deficit, and I've found that keeping carbs up helps prevent it.

I felt it the first few weeks. Magnesium helped me get deeper sleep. Staying well hydrated also cut down nausea and headaches, and I use electrolytes during workouts.

It happened to me early on. Makes sense after suddenly cutting food so much. It lasted a few months while weight was dropping fast but eventually faded. It goes away if you stick with it and keep protein intake up.

First week on Reta and fatigue hit hard. The change was obvious. I can barely lift what I normally do at the gym. It doesn't bother me much but I feel physically drained.

Yep, completely exhausted on just the starting dose with no energy. Weight is coming off and hunger is low. How are you handling your fatigue right now? Have you tried any vitamins?

I get very tired between 12 and 24 hours after a dose, along with brain fog. It passes fairly quickly but has been consistent so far.

Hard to tell since I'm always tired anyway, before and after Reta. If it hurts sleep then that would explain feeling more fatigued.

Completely true in my case too since every GLP triggered awful exhaustion plus zero ability to feel any pleasure. Everything seems far more normal after moving to that single milligram weekly upkeep amount. Only after the switch did I grasp how much they had been weighing me down.

I get fatigue and nausea for one or two days after the shot, worse when raising the dose. I moved my shot day so heavier workouts fall further away from it.

Definitely very tired, especially a couple days after shot day. I'm on 2.5 mg weekly and my husband on 4 mg sees the same. I use NAD+ for quick energy and Epitalon for sleep. Need enough food with protein and carbs. Also check if it's actual fatigue or anhedonia, which is another common side effect. I wasn't full of energy before starting anyway.

Would like tips on fighting fatigue. On 4 mg a week it hits within the first 24 hours after pinning. Probably because appetite is suppressed and I'm not eating enough calories.

This thread is useful. I've been microdosing 2.5 mg every four days since March, added 1 mg Tesa daily a couple weeks ago and Glow five times a week. Lost 30 lb in three months while training three times a week and had great energy until about a week ago when both energy and motivation dropped. Now I drag and feel brain fog plus constipation. Libido is fine so probably not anhedonia. Advice here points to calorie deficit or hydration, so I'll focus on those and maybe add carbs and fiber. Any other ideas from the group, including peptides? I was enjoying the high energy and want it back.

I don't get it. I started at 0.5 mg. Couldn't sleep the first and second night though.

Yes, 23F. I've had two doses, 0.5 and 1 mg each week. Didn't realize this was common until seeing the thread. Not sure if it's extreme but even espresso didn't help, still had brain fog and wanted to rest. Second shot was last Saturday and today (Friday) I finally have more energy. At least sleep and no constipation are fine, small wins.

Can't figure Reta out overall. Luckily I've been able to sleep in a bit, which offsets trouble falling asleep. Before increasing the dose I had great energy and motivation. Only at 4 mg a week and now very unmotivated in the morning. Skipping a run or gym leaves me in a funk all day. Calorie deficit probably plays a role but it's frustrating. Still don't regret it, just wish I felt as good as I look.

Tiredness shows up now and then. I keep up with my supplements, have four meals each day, and move around whenever time allows.