Jumping from Tirz to Reta - starting dose?

Got up to 12.5 mg weekly on tirz and it quit working. Sides were rough so switched to reta. Began at 2 mg and added 2 mg each week until reaching 8 mg. Now dosing 4 mg every 84 hours. Planning to go to 5 mg every 84 hours once the next supply shows up, then maybe 6 mg later. Hunger control feels stronger on reta than it did on tirz, though not sure if that's common. If reta stops working might add cagri.

Switched from tirz at 2.5 mg twice a week. Worried about sides so spread out about a dozen small 1-2.5 mg reta doses over 15 days to raise levels fast without overshooting. Readings pointed to glucagon signaling kicking in reliably around 6-8 mg weekly once steady. Added two more tirz doses during that period to manage hunger on days 4 and 11. Now six weeks past the switch with 19 total doses around 53-54 mg. Current dose looks like 8-9 mg weekly with no bad sides. Down 17 lb or 6.3 percent in 40 days. Tirz is usually seen as stronger for food noise, so why stop it for weeks if it was still helping?

Varies by person but 5 mg tirz gave stronger appetite drop and no food noise for me. Started lowering tirz while raising reta. Had stomach issues on tirz so went slower on reta. If sides aren't a worry then 2 mg start seems fine, jumping higher isn't ideal. With sides I'd begin lower and add 0.5 mg weekly. Only had about 30 lb to lose so effective doses stayed modest. Someone shared a titration chart that helped.

Hit goal after a year on 15 mg tirz. Dropped to 10 mg the next week then started reta at 1 or 1.5 mg, then 3 mg and stayed there. Stacked with 0.25 mg cagri until November, then stopped the cagri after dropping 15 lb past goal to avoid more loss. Mild hunger returned but stayed at 3 mg reta because easily full and still in deficit. Using lifestyle habits too since hunger isn't strong. Weight holding steady.

Am I the only one who takes both tirz 10 mg and reta 4 mg on the same day at the same time?

Easier to suggest a dose if I knew starting weight, BMI, and loss so far. Would just stop tirz and move to 6-10 mg reta after a week. With few sides on 15 mg tirz the higher switch dose could work. Bigger jump raises chance of bad sides so go slower if older or less healthy. Reta tends to raise heart rate and skin sensations more than same mg of tirz, plus maybe extra nausea. Peak blood levels hit around 24 hours after dosing and take a week to halve. Levels keep climbing up to four weeks after a dose change, which is why increases wait four weeks. For a fast equivalent swap the only semi sa

Bad experiences trying to rush titration when changing GLP-1s. Would stop tirz and start reta at 2 mg for four weeks, then 4, 6, 9, then 12 mg, raising every four doses. Not a race. Slow and steady, follow the study schedule.