One user reports running 20-25 mg tirzepatide every two days plus rotating additions of semaglutide, survo, elro, cagri and reta. They saw renewed weight loss and appetite control after stalling at lower doses, with only mild heart-rate effects from high survo and no major fatigue or blood-sugar crashes once adapted. Others express interest, caution about receptor burnout or side effects, and questions about scaling, stacking, and ancillary compounds like SS-31.
What this discussion establishesWhether tripling or quadrupling approved doses is reasonable versus risking permanent loss of response or serious side effects
Still openLong-term safety data and whether higher doses will remain effective or cause lasting receptor changes
Nothing here is advice.
I'm providing an update on my experience using 60 milligrams weekly of tirz. I'm still here and continuing my experiments. My current intake involves 20 to 25 milligrams of tirz every couple of days alongside 2.5 or 5 milligrams of sema during those administrations. Over separate weeks I tested additions of 6 milligrams survo, 6 milligrams elro, 2.5 to 5 milligrams cagri, and 6 milligrams reta. One observation from trying higher amounts of survo together with tirz is experiencing some heart palpitations, which shows it can happen despite claims otherwise. Survo seemed to lose its impact the fastest within one or two weeks. Elro stood out for maintaining effects longer than cagri, about double the duration per dose. Cagri performed adequately yet demanded large quantities to achieve the appetite control I sought. Despite these elevated amounts I haven't felt tired. My blood glucose stayed fine without any requirement to compensate for sudden decreases. I've begun shedding pounds once more and quit consuming those circus peanuts from the dollar general store.
You mentioned taking 30 milligrams weekly not long ago. What prompted such a large increase? Did you switch straight over to 60 or build up slowly after the 30? I'm also wondering if studies have been released about the recent Tirz experiments which begin at what I think is 25 milligrams.
I kept raising the amount until those constant cravings and intense appetite finally stopped, unlike what happened at the previous levels. Yeah some folks might think it was a stupid move but somebody needs to check how they actually perform in bigger quantities on a real person instead of test animals. Things look okay so far and changes are showing up after six months of zero progress from just going in circles so this time with bolder steps its finally paying off.
After more than three years using glp-1 I doubt those studies limited to twenty five would deliver strong results for me personally so larger amounts would probably work better
This is incredible. Ignoring the racing pulse, what about everything else? Maybe share the beginning weight, the present one, the goal weight, and any additional numbers you feel like sharing.
A few years ago my weight was 335. It took me around a year and a half to get down to 208. Later it climbed back up to 240. These days I'm sitting at 228 with a target of reaching 200 by November. Most of the side effects stayed mild except for one that really hit hard. I tried stacking a big amount of it onto the other medication just to check what happens but it seems like it won't serve as something to use ongoing, only for a short stretch of maybe a few weeks or a month.
Anyone else seeing stronger results against inflammation from bigger amounts?
my feedback here couldn't be reliable since i combine those items with this on a regular basis
That dose looks huge. I was panicking over my own step up to fifteen. I'll be checking in on how you do.
Alright, looks like figuring costs for those items is back on my plate. Will this be how things go from here on? Whatever, might as well roll the dice on it once more.
I’m using 120s right now and they are working for the higher doses. I’m going to switch to another 60mg option just to see if they have a difference on feels.
My main issue turned out to be glucose levels falling too low. At first when I took bigger amounts it happened a bit but after getting used to the substance it stopped occurring no matter how much I use.
I feel the producer ought to reach out for fresh medical studies on larger quantities of this stuff. Nobody can deny that taking sixty milligrams appears extreme for lots of folks, however my opinion is it wouldn't seem so bad if you factor in how officials okayed seven point two milligrams for the comparable product after it had been limited to two point four milligrams before. Given that they increased one by three times, there is no logic preventing doing three times or even four times with this medication.
My fear is that I might damage internal mechanisms so none of the alternatives would ever function again. Passing away is another thing that concerns me. Still I plan on staying awake right up until Brooklyn though. Keep the energy high.
I'm wondering what quantity of syringes gets used. Does it require a three milliliter one?
I find this quite intriguing. Did you think about including the pill form too? It attaches to those sites in a slightly different manner and might boost things for certain folks, especially since you're testing it on yourself. What about the oral version in those amounts?
You sure must burn through your stock fast! Right now I'm using 15mg tirz with 1mg Cagri, and I feel uneasy about hitting that upper limit for tirz while you exceed the usual maximum quite a lot. Seeing that you've pushed higher successfully is comforting. It eases my concerns if I ever raise my own amount.
Usually I add just a milliliter or two of liquid into each vial. Needles come in packs of five hundred and I grab several packs whenever I order.
thats why ss-31 is a must
This has shown up repeatedly in my circles lately yet the energizing sensations strike me as excessive since I already deal with enough of that stimulation daily.
Which standard is active for your ss-31 setup?
For a couple months now I've been taking between five and ten milligrams each day and honestly twenty milligrams doesn't seem to make any difference at all.
Started with the five milligram level yet found myself surprised by the amount of evidence pointing to forty milligrams instead, which turns out pricey. I was interested in learning your method for dosing Tirz when going higher. Thanks
I recently raised my dose to three milligrams since I'm experiencing zero appetite with this medication after six weeks. However, my sister has been taking fifteen milligrams for several years now and thinks it's no longer effective for her. I'll be keeping an eye on how things go for you.
Has she put the pounds back on or did the loss merely come to an end?
This guy always brings the band Molly Hatchet straight to mind!!
Appreciate you sharing details on elevated levels of that medication along with the rest. With studies missing completely, personal accounts found across forums remain the sole source of details on bigger amounts and mixes of these slimming compounds. A handful of people in situations like mine, facing serious weight problems or weak reactions to certain treatments, have no actual data to guide choices. Sixty milligrams of it does not come across as particularly high next to the semaglutide study reaching sixteen milligrams. Scaling the ratio from two point four to fifteen would suggest one hundred milligrams instead, though I suspect anyone reaching there must handle it quite well or else reactions would become overwhelming. At fifteen milligrams of the first one combined with six of the second, even one extra milligram of either leaves me feeling uneasy all over, so that marks my upper limit.
That's intriguing. This compound taken by mouth hasn't shown any ties to faster pulse or higher blood pressure in what I've come across, at least nothing comparable to certain stimulants. Bodies can handle things uniquely though, so your observation might check out.
It's partly both reasons though her eating slipped and she spread out the injections to hold onto enough for the relocation. She has restarted the fifteen milligrams each week and is now considering reta too.
Matters will resolve themselves. I am being lenient with myself while focusing on what I aim for personally 🙂
I apologize for acting like a typical male and cracking some crude bathroom jokes. I mentioned my eating plan leaving via the rear exit. The reduction in my body mass has followed a straight path.
Damn! That is some decrease!
Thinking about the half life aspect really leaves me uneasy. Your message honestly triggers that clammy hands reaction in me. 😱 Folks choose their own paths but this still catches me off guard!
Happy to know you're doing fine and keeping up the investigations. That high amount would probably leave me completely stopped up, with a laugh. My lower dose seems tiny by comparison. Appreciate the details on what you're trying now.
Benefits taper off sharply once the amount exceeds ten milligrams. Pairing it with comparable compounds strikes me as the better route.
😂 Looks like his setup already has everything it needs.
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