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Chronic fatigue

5 replies4 peopleMar 13, 2026☆ Follow
Summary

What regimens or compounds help with chronic fatigue, especially alongside autoimmune conditions like ITP?

Participants share personal experiences with fatigue linked to autoimmune issues and family health problems. One mentions exploring a peptide combination hoping for benefits, while another notes glutathione reduced infections but not tiredness. Discussion shifts to anemia management, iron absorption challenges after weight-loss surgery or aging, and the need for more frequent specialist monitoring rather than yearly checks.

What this discussion establishesWhere people disagree

Whether yearly lab checks and standard iron dosing are adequate for severe anemia cases

Still open

Which specific regimen or peptides actually improve chronic fatigue symptoms

Nothing here is advice.

5 replies · 4 people
KeenSignal56archiveopening postMar 13

What routine do you follow to handle ongoing tiredness? Has anyone dealt with ITP or similar immune disorders?

WarmSparrow81archiveMar 31

I’m checking out a peptide mix for several purposes, one being possible relief from this problem, though others have mentioned different peptides that seem to ease tiredness.

KeenAlder60archiveMar 31
↳ replying to @KeenSignal56 (opening post)

My mother dealt with CFIDS and I have Raynaud’s while my sister has Devic’s syndrome. I tried glutathione at 2000 mg daily for seven days a week because I kept getting ill; it stopped the constant sickness for more than a year but did nothing for fatigue. Mom passed in 2010 and my sister shows little interest in peptides since she considers herself fairly healthy aside from a stubborn UTI lasting over a month, repeated kidney stones, and anemia severe enough for transfusions. I should remind her about her iron intake and other steps.

CopperSignal27archiveMar 31

If anemia has reached the point of needing transfusions, it is difficult to picture that iron levels are not being monitored and that guidance on supplements is not already being given.

KeenAlder60archiveMar 31
↳ replying to @CopperSignal27

Many physicians recommend ferrous sulfate, yet after weight-loss surgery or with age stomach acid may be too low for proper absorption, so polysaccharide iron complex is needed and apparently at higher amounts than one tablet three times weekly. My own hematologist had me take it on Monday, Wednesday, and Friday along with at least 200 mg of vitamin C each time during my infusions last fall. I previously used it daily without the vitamin C and am awaiting six-month labs to decide if two tablets on those days are required. My sister skips hematology and endocrinology visits, so her iron is checked only once a year, which is why levels drop low enough for transfusions. She asks my input for others but dismisses it for herself despite my nursing background, which is frustrating.

CopperSignal27archiveMar 31

Transfusions paired with annual testing does not seem like the best approach. I have a daughter who ignores my medical suggestions so I understand the situation somewhat. It feels pointless to miss school and use pain relief for migraines when other options could resolve them faster, yet that is how it goes.

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