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Weirdest/most annoying side effect?

15 replies16 peopleOct 14, 2026☆ Follow
Summary

What weird or annoying side effects have people noticed on this medication?

Users report a range of persistent or surprising effects including nasal drip, skin crawling or sensitivity, sudden diarrhea, chills, allodynia, and constipation or the opposite. Some effects fade with time or lower doses while others remain stubborn or appear only after certain triggers like restaurant meals. A few participants note they enjoy certain sensations or see no downsides at all.

What this discussion establishesWhere people disagree

Some enjoy skin sensitivity or report zero negatives at 6 mg while others find allodynia or GI issues debilitating; a few experience the opposite sinus effect (dry vs. drippy).

Still open

Whether certain effects like mood filter loss stem from the medication, aging, or both

Nothing here is advice.

15 replies · 16 people
LevelThistle60archiveopening post1d

The runny nose stands out most for me. Tingling sensations and chills eventually eased up, yet the drip has hung on stubbornly and caught me by surprise.

GreyAlder77archive1d

Crawling skin hit me hardest at bigger amounts, though I adjusted to it eventually and it vanishes on my current lower amount. Chills come in right behind that.

SharpCinder28archive1d

Your nasal drip is nothing; I counter with sudden explosive diarrhea.

At 6 mg I feel no downsides at all. The skin sensitivity feels good to me and my midsection looks better too.

GreyThistle69archive1d

I get the nasal drip too but figured it was just my usual hay fever acting up, since I react strongly to pollen and deal with it constantly.

IronLantern24archive1d

The sulfur burps stand out for me.

Loose shirts now look odd on me, that’s the first thing that comes to mind.

Sudden urgent diarrhea with almost no warning has been the worst surprise, though it happens less now; early on it startled plenty of people around me.

RustTimber42archive1d

Opposite experience here: my sinuses go completely dry for the first couple days after each injection.

ClearQuill84archive1d

Allodynia turned out rough after I accidentally injected 9 mg instead of 6 mg; the body aches lasted a full week along with constant chills and feeling frozen.

Allodynia is miserable, plus this sparkly itch right in the middle of my back that seems tied to it; both cleared up after a few months.

WryFenwick45archive1d

My usual restraint around saying dumb things to people seems gone now; hard to tell if that came from the medication or simply another year of age.

GreyLantern71archive1d

Constipation shows up with my usual home meals while anything from a restaurant flips it to diarrhea, with nothing in between. Nasal drip also appears a few days after each shot.

GreyPebble44archive23h

Bone-deep cold that layering never fixes, always feeling chilled.

QuietSparrow66archive23h
↳ replying to @GreyPebble44

Same here; I now sleep on a large heating pad and it feels really good.

LevelAlder34archive20h

Anhedonia creates a strange mix of feelings I both appreciate and dislike.

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