Penta agonist weight loss stack? Tirz x Reta x Cagri

I'm doing exactly that on a six-day schedule with a shot every two days. I started it to get past a stall, first on tirzepatide, then added cagrilintide, then retatrutide. Cagrilintide hasn't affected me the way many others describe. I went up to 10 mg tirzepatide every six days over four months and began getting tinnitus and prickly skin, so I stopped raising that dose. I had already dropped 40 lb by then, but hit a month-long plateau. Adding 500 mcg cagrilintide every six days changed nothing. Adding 1 mg retatrutide every six days also did little. Raising both to 1 mg cagrilintide and 2 mg retatrutide still barely moved the scale. Only when I reached 2 mg cagrilintide and 4 mg retatrutide alongside 12 mg tirzepatide did the loss restart. The first two nights after that increase the skin sensitivity was bad enough that I considered stopping everything. It has eased a bit since.

I'm also thinking about adding cagrilintide for hunger control. Tirzepatide for eight weeks gave me nothing, so I switched to retatrutide. Still nothing, though it's only been six weeks. Neither one has quieted the food noise and it's frustrating. I'm trying to stay patient but it's really hard.

Wouldn't tirzepatide and retatrutide overlap on some of the same receptors? It looks like you're doubling up on GLP-1 and GIP without much point. Why not just run retatrutide with cagrilintide and drop the tirzepatide?

The tirzepatide stall lasted about a month. After adding cagrilintide there was still no movement, then retatrutide went in a month later. I lost five more pounds before stalling again. Three weeks after that I raised the doses and dropped two more. Even at 2 mg cagrilintide every six days it does nothing for me—no loss, no appetite change, no sides. Even if the scale stays put from here, the 55 lb total loss in seven months has been worth it, almost all from tirzepatide alone. If the water-retention theory is right, results should show once things settle or during the next break from the other compounds. Patience isn't my strong point.