No RegreReta.

85 kg sits in the healthy BMI range for your height and would be about a 19 percent loss. Some trial participants lost up to 28 percent. The 0.5 mg starting amount is mainly to check tolerance; you can move up fairly quickly to 2 mg if all feels fine.

You could try another 0.5 mg shot four days later if there are no side effects and appetite has not changed yet.

0.5 mg is too small an amount. Begin at 2 mg for four weeks and then reassess. How are you even measuring 0.5 mg without a tiny syringe?

I chose 0.5 mg to see how my body handles it first. Results matter, but I want the smallest effective amount with the fewest issues. This is my first time with any peptide, so I am being careful. Several threads here suggested the same approach.

I am on week two at 0.5 mg and like the idea of the lowest effective amount. I may move to 1 mg in week four.

Starting at 0.5 mg seems pointless; 1 mg at least matches half the usual trial starting dose. Very low doses do not stop side effects from appearing later when you reach the amount that triggers them. It may only delay when they show up. For nearly 20 percent body-weight loss you will probably need higher amounts, though some lighter people do well on 2-4 mg.

After reading about someone ending up with bad nausea and vomiting on a low dose of a similar medication and considering the ER, I see little downside to starting slow except losing a bit of time.

First week: started at 104.9 kg, now 103.6 kg, down 1.3 kg. I have added some running and gym time. The loss is probably water and glycogen at this stage. No real effects or side effects from the shot yet, though I am choosing better foods. Dose increased to 1 mg today. Question: how long can a reconstituted 20 mg vial stay usable in the fridge inside the pen?

Official guidance says no more than four weeks refrigerated. Longer storage raises the chance of contamination even with careful technique. Most people here do not report problems up to two or three months, but there is always a small infection risk.

Second week: 103.6 kg to 103.4 kg, only 0.2 kg down. I was traveling and ate some convenience food while missing a couple of workouts. Still no strong appetite changes or side effects beyond slight fatigue on dosing day. Increased to 2 mg this week.

Another thread mentioned a batch that may have been labeled double the actual strength. My batch number matches. Some tests on the same batch look okay, others do not. I am unsure whether I am actually taking 2 mg or only 1 mg, which might explain the mild response so far.

Last week started at 103.4 kg, now 101.9 kg, down 1.5 kg. I took 2.5 mg today because effects seemed to be fading. Planning to stay here for a few weeks if loss continues. Felt the usual half-day fatigue and brief nausea while eating. Exercise is improving with 11 km running this week.

This week: 101.9 kg to 100.7 kg, down 1.2 kg even after starting creatine again. Ran another 11 km and spent 3.5 hours lifting. Side effects included more fatigue, low mood, and noticeable nausea for the first couple of days. Still sticking with 2.5 mg for now.

I also began low: 0.5 mg week one, 1 mg week two, then 1 mg twice weekly by week four. Appetite dropped quickly and I had to remind myself to eat protein. Now at 2-2.5 mg twice weekly. Weight has come off steadily with occasional small rebounds. Main side effects have been skin sensitivity, feeling cold in the evenings, and facial changes from fat loss. I started another supplement a few weeks ago to help with skin appearance.