The health gains from these medications are concrete especially if you're closer to facing those risks yourself. The combination I'm on has helped my physical and mental side along with likely adding years. Testing puts my chance of serious heart issues or worse around twenty to thirty percent in the next decade even with current meds and stable weight. At my age that's not great but gaining back the weight I lost would make the odds much worse and probably cut short any decent health span.
It can go both directions. Some people handle being alone fine while others struggle. Not everyone needs the same level of social contact. Introverts might not get the same lift from it. The loneliness issues among older adults often tie to losing a long term partner. It still doesn't tie back to the original topic though. Healthier men might have more energy for social stuff if they want it.