Hey, I began with Reta early this year at 0.5 mg twice a week and got solid results. Toward the end of my diet I raised it to 0.75-1 mg twice weekly but it stopped working like before. I figured I'd quit and start reversing my diet, yet hunger and appetite came back way stronger. Should I go up again? I'm considering 1.5 mg twice a week. Any better options? Thanks for any help, have a good day or night.
Not feeling anything at all anymore? Reta on a diet.
Summary
How to handle fading appetite control from retatrutide when starting a reverse diet after weight loss?
The original poster lost good weight on low twice-weekly doses but saw effects drop at the end of their cut; stopping led to strong rebound hunger. Others recommend titrating higher, with one user now comfortable at 6 mg weekly after side effects faded and another at 3 mg every 3.5 days. Personal results vary but several note stronger effects around 4 mg and above without major issues once tolerance builds.
What this discussion establishes- Initial low doses worked well then lost impact, prompting thoughts of stopping
- Twice-weekly schedules mentioned more often than once-weekly
- Users report reaching 4-6 mg before consistent appetite control returns
- No side effects seen as green light to increase dose gradually
- Weight loss continued steadily for some after finding their effective level
Best day spacing or exact target dose for someone already at 1 mg twice weekly with zero current effects
Nothing here is advice.
6 replies · 4 people
↳ replying to @IronLantern24
Hmm what dose should I try? Maybe 1.5 mg twice per week? And on which days, like Monday and Thursday? Or just once a week on Wednesday?
Welcome. I can't really help with your question but here's how I started. After the first 2.5 ml I stayed at 0.5 ml once a week for roughly six months and lost 4 lbs every week without fail. Hit a plateau so I moved to 0.8 and now I'm at 1.0. To me your twice-weekly shots should already be enough. Hopefully some of the more experienced people will reply. Wish you the best.
↳ replying to @IronLantern42 (opening post)
If you have no side effects it's fine to titrate up until you find what works. A lot of people here say effects really show up around the 4 mg mark with reta. Same thing happened for me. I began on April 11 at 1 mg once a week and felt everything the next day including nausea, headaches, strong appetite suppression and skin sensitivity. After two weeks on 1 mg the sides disappeared so I kept going up and now sit at 6 mg where I'm comfortable, dropping 1-2 lbs weekly with good appetite control and no food noise. Down 17 lbs total since April from 205 to 188. Hope that helps your own progress.
↳ replying to @IronLantern42
Yeah, try that. I've been on it since 1/5 and I'm up to 3 mg every 3.5 days now.
↳ replying to @NorthBramble10
I'm really happy for you, that's a huge amount of weight lost already! Started in January myself and dropped 44 pounds. Now I'm trying to raise calories a little so appetite has gotten worse and I need to keep it in check. Since I'm not getting any sides or even any effects at all I think I'll titrate up. Thanks!
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