Tirzepatide + weed — anyone else deal with this?

With retatrutide I get the same thing and it passes after I eat a couple complex carbs. Two crackers usually takes care of it.

Same experience here after seven months on tirzepatide and several months using THC gummies and then smoking. I am trying to cut back to twice a week. When the munchies hit I reach for carrot sticks or low-calorie crackers and anything crunchy but low in calories. The urge feels a bit weaker than it used to be but it is still present and sometimes adds about 150 calories to the day. On nights I plan to use cannabis I eat lighter earlier.

My father-in-law takes tirzepatide for diabetes and weight loss and uses cannabis every Friday. Every Saturday he says he regrets it because the cannabis wipes out the food control and he eats heavily.

I have not seen that effect. I use cannabis heavily and never really got the munchies from it anyway. It mainly helps with aches, pains, and mood. I have not noticed any change since starting tirzepatide. Maybe the answer is to use more cannabis, though that is only half serious.

I use one pre-roll daily and it keeps the doctor away. Cannabis was the original peptide.

There is a lab study on how cannabis affects hormones tied to appetite. It showed a trend toward changes in GLP-1 and clear effects on other hormones, especially insulin. The conclusion noted that cannabis modulated concentrations of appetitive and metabolic hormones, chiefly insulin, in users.

Ayo waddup Stavvy!

I used cannabis for 45 years before starting tirzepatide at age 59. The day I began the medication I quit smoking. Reading these accounts makes me think that was the right call. One nice side effect is that I have no cravings for cannabis now, similar to how sugar and beer lost their appeal. I may just be lucky, but I really like tirzepatide.

Glad to see this thread. I live where cannabis is fully legal and I am a heavy user. In the past it caused weight gain because everything tasted great while buzzed. I expected to have to stop during weight loss, but instead tirzepatide completely removes the munchies for me even when I use THC. Reactions to both substances differ, and in my case the hunger while high is gone.

I am a larger person and have been using gummies for stress relief. Regular THC, both indica and sativa, always made me want to overeat. Then I tried some indica-dominant products with a 5-1-1 ratio focused on CBG. They help me relax and I usually fall asleep after a couple hours without getting hungry or overeating. Might be worth trying.

Tirzepatide stops working for me when I vape cannabis. I try to manage it with healthier choices.

A buddy of mine won't stop saying that this medication isn't doing anything for her. She's still early in the second month and plans to raise her dose to six milligrams on a five-day cycle. Plus she uses cannabis every single day and has a job at a tavern that serves lots of food. At times it's impossible for the treatment to overcome the daily habit, so a choice has to be made.