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Affordable weight loss medication production and US patent issues

12 replies9 peopleMar 6, 2026β˜† Follow
Summary

Why are weight loss drugs like semaglutide so expensive in the US despite potential low production costs elsewhere?

The thread discusses an article on low-cost production of semaglutide and contrasts it with US pricing and patent practices. Participants agree that extended patents, corporate strategies, and lobbying keep costs high domestically even after expiration elsewhere. They note big pharma profits and regulatory influences but differ in tone from factual to sarcastic.

What this discussion establishesWhere people disagree

Some see legislative actions on peptides as probably influenced by industry while others state it as definite fact.

Nothing here is advice.

12 replies Β· 9 people
AmberPebble48archiveopening postMar 6

This is positive information reported by the Guardian. I didn't expect the lack of patents across Africa!

WarmMeadow92archiveMar 8

Pieces such as these make me realize the messed up situations that exist here. Laws around patents let large firms prolong their protections in multiple ways so citizens end up spending more and more over time. Even once a drug's protection runs out agreements between companies along with their focus on profits keep costs elevated in unnatural ways. One case shows a medication whose protection ended a couple years back available at lower cost abroad yet still expensive on a monthly basis in this country. High quality generic versions of certain compounds are unlikely to ever reach truly low prices in this market.

LevelTimber64archiveMar 8

Yeah I realize they spend enormous amounts on their studies with plenty failing to become actual products or help anyone. Yet seriously.

AmberBeacon65archiveMar 8

Those big drug firms are gonna keep stacking up patents around different features of the meds so they can hang onto their grip over sales and pull every last bit of cash from folks.

WarmMeadow92archiveMar 8
↳ replying to @AmberBeacon65

I figure politicians back the push to restrict these compounds because major drug firms applied some pressure.

BlueTimber78archiveMar 8
↳ replying to @WarmMeadow92

In my opinion that particular word isn't essential and can be left out.

SlowBramble78archiveMar 8
↳ replying to @WarmMeadow92

The drug companies' push for shedding pounds runs like a hyped-up casino setup where the deck stays stacked against you. Those enormous shiny gambling spots weren't put up because players kept leaving with cash in hand each time. The owners rake it in over extended stretches while all the bright attractions pull the marks or rather the people getting treated back in repeatedly.

WarmMeadow92archiveMar 8
↳ replying to @SlowBramble78

Casinos never bother claiming they want to keep anyone in good shape or anything like that πŸ˜‚

LevelThistle44archiveMar 8
↳ replying to @WarmMeadow92

Not sure why but this wellness check happened lately and it really bothered me.

SharpAnchor92archiveMar 8

It's surprising the report gives such a low figure for the monthly cost of semaglutide within the country. I remain convinced the actual amount stays much greater per month regardless of coverage and without factoring in those early limited promotions.

LevelFenwick35archiveMar 8
↳ replying to @LevelTimber64

Figured I would post this update. The figure really is in billions. One large medication company showed excellent performance over the full year of 2025, reaching 65.2 billion in total sales, marking a 45 percent rise over 2024, plus 20.6 billion in final earnings. The increase mainly resulted from big interest in products addressing diabetes along with excess weight concerns, as those items generated 36.5 billion combined.

LevelTimber64archiveMar 8
↳ replying to @BlueTimber78

I went and took out think from there with no issues either πŸ«£πŸ˜‡πŸ˜†

LevelTimber64archiveMar 8
↳ replying to @SharpAnchor92

Seems you overlooked the small text. It specified the monthly amount for that medication here gets listed using dollars from 1901.

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