CommunitySide Effects

CAGRI Overdose???

28 replies12 peopleMay 10, 2026☆ Follow
Summary

What happens after an accidental 3.75 mg Cagri dose instead of Tirz and how to manage the resulting nausea and vomiting

A 65-year-old woman received 3.75 mg Cagri by mistake and developed severe nausea with repeated vomiting that lasted into the next days. Participants advised monitoring for dehydration, offering small sips of electrolyte solution, bland foods if tolerated, and OTC or prescribed anti-nausea medication. Several stressed going to the ER if dizziness, weakness, or reduced urine output appear. The incident prompted discussion of better labeling and storage practices to avoid future mix-ups.

What this discussion establishes

Nothing here is advice.

28 replies · 12 people
PatientAnchor11archiveopening postMay 10

I wanted to chime in on this thread. My spouse ended up getting 3.75 mg of that Cagri mixed in bacteriostatic water by mistake instead of the usual 7.5 mg Tirz the day before. Right now she feels extremely sick with ongoing throwing up and retching even when nothing remains. Which possible issues do I need to keep an eye on and how might I help reduce her unease. She normally handles most of the household support so this situation falls outside what I usually deal with. Any input would be welcome. I set out plain water plus some electrolyte drinks for her to take small sips from. So far she never had reactions while increasing the Tirz amount. She tends to react strongly when medications combine. This marks the first time she has encountered Cagri. The dose came from a 5 mg vial mixed with 1 ml of that water and we skipped the Tirz today.

PatientQuill20archiveMay 10

Without any background handling Cagri that amount seems quite elevated from what I understand. Nausea probably reaches its highest point by day three with unease continuing through the following week or beyond. Staying hydrated along with electrolytes seems helpful. Plain items like toast without toppings simple rice biscuits or clear broth might ease things if she manages them. Simple meals work well yet forcing intake isn't necessary. Staying active matters so short strolls could be useful when possible. Others might share more thoughts too. These thoughts cover typical reactions to strong queasiness.

SharpCinder28archiveMay 10
↳ replying to @PatientAnchor11 (opening post)

I reached out through a virtual visit or my regular physician to obtain a prescription anti-nausea medication. For someone based in the States, certain insurance options cover those remote appointments without any charge. In the short term I turned to non-prescription remedies to handle the symptoms. The usual choice is the non-brand form of that drug, which came out inexpensive when I used a discount card at the drugstore.

PatientAnchor11archiveMay 11
↳ replying to @SharpCinder28

I keep some pills stored away at home. Placed one beneath my tongue hoping it would take effect. Continuing to drink only plain liquids. Nothing remains in my stomach. Bringing up only transparent digestive liquid. Appreciate it.

SharpCinder28archiveMay 11

Whenever someone feels really sick or keeps throwing up, heading straight to emergency care makes sense to me. There's no reason to suffer when they can hook up fluids and give shots for relief right away. Acting early seems smarter than waiting for things to get worse. If the reason behind it makes someone hesitant about doctors, mentioning an accidental too-much of the mixed medication could work as an explanation. Still, telling the truth tends to work out better when things look bad.

CopperSignal27archiveMay 11

From my experience the biggest problem during bouts of throwing up or stomach illness comes from losing too much liquid since holding it down proves hard amid the sickness. When that loss starts happening it's time for an in-person visit to a physician or urgent care. Weakness, lightheadedness upon rising, sunken cheeks and areas below the eyes, rapid pulse, or just overall poor condition all point toward needing assistance right away. Hospital stays with intravenous liquids become necessary once dehydration gets bad. Reduced urine output serves as another indicator. Pushing things too long risks kidney issues so caution with getting checked makes sense. Pharmacy electrolyte mixes meant for children during digestive troubles work better than plain water or athletic beverages because they get taken up quicker. Sipping tiny quantities frequently every ten to fifteen minutes helps. This approach has kept some kids from needing drips even while sick. Continuing to vomit doesn't always stop getting some in. Should the situation drag on for multiple days medical attention feels wiser particularly when nausea medications fail to assist. Mistakes in measuring amounts turn up often as the main trouble with research peptides so I always verify the math multiple times using a web based tool and mark all containers clearly with the substance details concentration and standard amount.

SharpCinder28archiveMay 11

I read about a medical case involving an unintended excess intake of liraglutide. Doctors administered fluids through a vein along with metoclopramide delivered the same way. The same medication was later tried during an episode of persistent hiccups triggered by another compound in that class, but it provided no relief.

QuietSignal61archiveMay 11
↳ replying to @SharpCinder28

Yeah it's not ideal for anyone involved yet we still need to factor it in. Hey OP I can't share much here but balancing salts and minerals comes across as the main issue. Blending protein into drinks along with crushed ice and berries might turn out useful down the line. It settles easily in the stomach.

PatientAnchor11archiveMay 11
↳ replying to @QuietSignal61

Feeling quite good now. The throwing up has ended. Sipping liquids and having some broth. Appreciate all the responses.

SharpCinder28archiveMay 11
↳ replying to @PatientAnchor11 (opening post)

There was a time when I mistakenly used the incorrect container as well, yet it turned out to be just BPC. Much like the other blunders I've committed throughout my years, I wasn't paying attention at all. Seeing your comment has made me question how I handle things now, and not only by moving at a reduced pace. Examples include keeping items separate instead of together and making sure the markings don't match in appearance. I've decided to switch back to using tiny boxes of various shades to store the containers inside the cooling unit, ones that hold a single container each.

PatientHarbour23archiveMay 11

Whoa this one packs way more punch than I expected so a quarter milligram should be the absolute starting point. Half a milligram left me miserable so I dropped down near a third yet the effects still lingered a bit. I grabbed some nausea tablets and kept drinking tons of water.

SharpCinder28archiveMay 11

Another OTC product at stores for nausea from GLPs.

IronLedger65archiveMay 11

If you filter, try putting them in different sized bottles.

SteadyTimber49archiveMay 11

That must've been tough to deal with. Glad she could hold onto some liquid today anyway. Hoping she recovers fast after such a hard experience.

PatientAnchor11archiveMay 11
↳ replying to @SharpCinder28

I agree with that. Earlier I prepared a container holding one substance at a certain concentration and administered half a milligram from it a single time. I neglected to mark it right away before storing it cold, thinking I'd move the leftover amount into my fresh injection device. When fetching our weekend supply of the other substance—mine already loaded in its device and hers still in the bottle—I mistakenly selected the unmarked one instead. It's marked properly now. I really hope that incident didn't put her off these types of treatments entirely. She took her time deciding to try the medication and only did so without any urging from me. If only I could convince her to handle the injection device herself for her doses. Two new nice-looking devices are arriving soon.

SharpCinder28archiveMay 11
↳ replying to @IronLedger65

With a larger vial I could add more liquid to thin out the medication, requiring a greater number of units before reaching an overdose level. The replacement product calls for increased amounts compared to the current one, giving yet another cause to make the change down the road.

PatientQuill20archiveMay 12

When I store peptides inside containers I bought an assortment of differently hued tops to match the stickers. I assign each kind its own shade on the top. That approach makes it simpler for me to avoid mix-ups. Still I glance at the sticker to confirm.

PatientAnchor11archiveMay 12
↳ replying to @PatientQuill20

I already possessed tinted lids and put them to work so each container now carries exact markings. It counted as one of my foolish personal habits... Gratitude

PatientAnchor11archiveMay 12
↳ replying to @QuietBramble77

Appreciate you checking in. She's getting better and returning to her habit of pushing too hard. Earlier today she rose ahead of me, shifted her illness items onto the living room couch, grabbed some chilled water and has been sipping it while taking small bites of sourdough bread I prepared at her request. She rests for long stretches, produced a bowel movement and emptied her bladder multiple times. She asked me to warm some canned chicken noodle soup yet found the flavor strange. The queasiness passed and she's holding down both the water and the toast. Everything stemmed from my mistake. That substance was mine, I mixed a vial at five milligrams per milliliter then hurried to test it on my rodent without labeling it or telling her and left it in the fridge. On our usual weekend morning injections she took seventy-five units of it by accident instead of her normal dose. Vomiting started about half a day later and her state worsened after that. It really shook me since I'm not one to frighten easily. My comfort with risks runs much higher than hers and I even considered going to the emergency room. Thanks for inquiring about how she's doing. Also a huge thanks to everyone who pointed out things worth watching.

PatientAnchor11archiveMay 12
↳ replying to @PatientQuill20

Thanks for the suggestion. Three pens marked with separate shades keep my supplies organized. Brown holds the insulin my doctor keeps cutting back on until this final one runs out. Yellow tracks one compound and gray the other I only began recently. A bundle with several doses plus two extra devices arrives soon. Looks like I'm turning into quite the fan of these substances. Everything gets covered by skipping my usual big nightly serving of frozen dessert and that's no lie.

WryFenwick45archiveMay 13
↳ replying to @PatientHarbour23

This stuff hits with insane force. Weeks in and half a unit still feels totally manageable, which actually makes the whole thing seem like a solid value. I have no idea how anyone could handle the amount that guy's spouse went through. Whoa!

PatientAnchor11archiveMay 13
↳ replying to @WryFenwick45

It's the third day now and this morning she's improved quite a bit. She woke earlier than me to feed our stubborn dog. She wanted some toasted sourdough she had baked herself, split in two with peanut butter on one side, and ate it slowly until it was all finished. Next she asked for a cherry popsicle which she managed to finish, though she said consuming so much left her tired and she returned to sleep with the dog that I couldn't keep away from her bed. All seems good... Thanks.

RustMarble10archiveMay 14

It's such a relief to hear her health has improved. The whole ordeal must've felt frightening.

WryFenwick45archiveMay 15

So relieved to hear your wife is okay.

SharpTimber40archiveMay 15

I'm glad she's okay. 5 mg Cagri is no joke. I went up to .8 today and I'm feeling rough.

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