Tirz for BED

If your main goal is just quieting the food noise, cagrilintide might be worth looking into instead.

There’s nothing wrong with testing a tiny amount of any new substance first to see how your body handles it. It could have an effect or it might not register at all. I started small myself because I was worried about a possible allergic reaction.

Your BMI is already 18, which means you’re underweight. Adding peptides on top of that puts your health in danger.

I’ve been microdosing tirz at 1 mg a week, split into two 0.5 mg shots. I didn’t have much to lose and was only four pounds from my target. I intend to keep using the low dose ongoing so I don’t have to stress about regaining five or ten pounds. Plenty of people stay on tirz once they hit goal weight, so this would be the same idea but aimed at maintenance.

At your low weight it sounds like you’re already restricting quite a bit even while dealing with binges. That pattern can make the binges stronger over time. I went through the same cycle for years. Eating three solid meals plus decent snacks every single day can help your brain feel safe again. Make sure you aren’t undereating. A small dose of tirz might ease the mental chatter, but if your body is already underfueled the situation could get worse, so proceed carefully.

I expect tirz will eventually be shown to work well for binge eating disorder. There are current studies on tirz and addiction, and I’ve long thought BED fits better in the addiction category than with other eating disorders. I’m a clinician in this area and have dealt with it myself. The constant food thoughts and needing to overeat to feel full were ongoing problems. Tirz shut that down right away. I had already handled the behaviors, but the mental side only improved once tirz arrived. Start low and increase slowly until you find what works. Two caveats: this is for BED only; any other eating-disorder issues make it more complicated, and you should be working with a therapist either way. Also, I’m a therapist but not yours, so none of this is clinical advice.

Using GLP drugs at a BMI of 18 sits right next to the anorexia nervosa cutoff at 17. Even if you don’t think you have that issue, it’s common for people with anorexia to feel the same way. Getting expert input first would be wise before trying this route. Any real reduction in eating or binging is likely to cause weight loss too. These drugs may eventually be used for BED, especially when obesity is present, but the evidence isn’t solid yet and most professionals probably wouldn’t be comfortable with it at such a low BMI. If purging were involved it might be different, but professional guidance would still be safer. They’ve helped my own BED when combined with a structured diet, though I started at 145 kg.