Wellbutrin+naltrexone

I recognize that pattern too and probably have some undiagnosed attention issues myself. I currently take the combination product as well, just one tablet in the morning at the moment. It acts through the melanocortin route that affects hunger and fullness signals. It does not seem especially strong by itself for dropping weight, yet it does appear to ease the kind of cravings you described. For many people reta does not suppress appetite very effectively either. Still, your other numbers look solid.

Both drugs are psychiatric medications. Naltrexone is approved for alcohol and opioid cravings and is sometimes used off-label for other compulsive behaviors. Wellbutrin is an NDRI prescribed for depression, seasonal mood issues, and quitting smoking, with off-label use for attention problems. The two together form the approved weight-loss product. Anyone considering them should expect the usual psychiatric warnings around anxiety and suicidal thoughts and should track their own mental state closely. I would not have tried the NDRI without a prescriber overseeing it and first adding mood and anxiety support, because without those I could not sleep and had severe panic. Naltrexone quickly pushed me into deep low mood so I stopped it.

The pair did nothing for me and I simply continued overeating while on the NDRI. Hair loss is another possible effect to watch for. Low-dose naltrexone at levels below the weight-loss combination is supposed to carry other health upsides, so I may finish what I still have at that lower amount instead.

I have already described elsewhere how naltrexone and tirz compared for my alcohol urges, with the latter working better. Years earlier I also used the NDRI to stop smoking and found it unpleasant, with intense dreams and confused waking thoughts. Seeing the two drugs combined for weight loss immediately raised concerns for me. In my own experience tirz has been the most reliable way to quiet sugar cravings.

From the replies so far no one has described the combination as particularly effective. The sample is small, of course. I have never taken either medication before, so I started the NDRI by itself to check tolerance. Some leftover extended-release tablets at 150 mg have been used for about a week now. Motivation and energy may be slightly better but overall I notice little difference and no appetite shift. The naltrexone component is supposed to block the reward pathway that the NDRI turns on. Assuming no manic reaction appears by the time the generic version arrives, I plan to begin at 90 mg and 8 mg.

Before trying tirz I used a mix of the NDRI, naltrexone, and metformin. A few pounds came off but I had to drop the naltrexone after side effects appeared, including numbness on half of my face. The prescriber said it was recognized and might fade, yet I did not want to continue long enough to find out. Hope your choice works out without that issue.

Thanks. Out of curiosity, what amount of naltrexone were you using?