ForumDosing & Titration

Triz upped dose now more hungry

7 replies5 peopleJun 17, 2026☆ Follow
Summary

why does raising tirzepatide dose sometimes increase hunger and calories eaten while weight loss speeds up

Several users report that moving from 3-7.5 mg to 6-10 mg brought back noticeable hunger and higher daily intake yet produced faster or resumed weight loss after stalls at lower doses. One person tracked a jump from 1600 to 2400 calories alongside dropping from 198 lb to 180 lb in six weeks. Others describe similar shifts at 7.5 mg where appetite returned but loss continued at 2 lb per week. No clear mechanism is agreed on; suggestions range from GIP effects or resolved insulin resistance to simple fluid shifts or measurement error.

What this discussion establishesWhere people disagree

whether extra calories can physiologically drive greater fat loss or if the reports reflect short-term water-weight changes or dosing mistakes

Still open

what actually explains the reversal from appetite suppression to increased hunger plus faster loss at higher doses

Nothing here is advice.

7 replies · 5 people
SharpHarbour92archiveopening postJun 17

I stayed on 3 mg of triz for several months and the weight came off gradually while my appetite stayed low. I was eating roughly 1600 calories with 160-170 g of protein and the balance from carbs and fat. After moving up to 6 mg over the last two months I suddenly feel very hungry and now take in about 2400 calories yet the scale keeps moving downward. At the lower dose I had hit a plateau even though I wasn't hungry. It's odd that the bigger dose lets me eat more and still lose faster. Triz has also evened out my blood sugar, cleared a toenail fungus, quieted a lot of negative self-talk, and now lets me eat bigger portions. Anyone else seen this pattern?

AmberBeacon78archiveJun 17

I'm also dealing with food noise returning. I had been on 7.5 mg for about six weeks and was averaging 2.5 lb lost each week. Around week five the noise started coming back, so after week six I moved to 10 mg. Even at 10 mg the noise feels noticeably stronger than before. Weight is still coming off, better than with no tirz at all, but I'm not sure why the change happened. Everything came from the same batches.

CopperSignal27archiveJun 17

Over what stretch of those two months did the weight come off and how much? Nothing you've described has a straightforward explanation. Adding roughly 800 kcal a day almost never produces more weight loss, though short-term fluid shifts could create the appearance of faster loss. Is the tirz from the same batch? Have you checked your mixing and dosing math several times? What happens if you raise the dose again?

PatientFenwick55archiveJun 17

Yes, the same thing happened to me. I felt very nauseous on 2.5 and 5 mg and could barely finish a meal. At 7.5 mg I started eating three times a day and had more energy, yet I still dropped about 2 lb a week and lost nine pounds that month. It wasn't food noise exactly; I got hungry but nothing sounded good. My doctor guessed the dose was finally fixing my insulin resistance. I'd suggest staying on this dose until you stop losing.

SharpHarbour92archiveJun 17
↳ replying to @CopperSignal27

I'm wondering whether the GIP part is becoming more active at the higher dose. All my triz comes from a well-known U.S. pharmacy. It still doesn't make sense to me either. I began in November at 211 lb, dropped 11 lb in the first three or four weeks, then stayed between 195-200 lb for two months. Once I went to 6 mg and raised calories from 1600 to 2000 the weight started moving again and I went from 198 lb to 180 lb in about six weeks. The last two weeks I ate 2400 calories and still went from 185 lb to 180 lb. It's really interesting that I can eat more than I have in years and keep losing. Triz has been a game changer overall. ChatGPT suggested my body finally feels safe so it's releasing the extra fat. I started at 28 percent body fat and now I'm at 18 percent.

CopperSignal27archiveJun 17

I accept that what you describe actually occurred. I still don't have any physiological explanation for how eating more calories could produce greater weight loss. I've seen similar stories before and have always been doubtful. You did raise calories quite a bit and saw solid loss, though. In everyday terms, losing while eating more should make the whole process easier. Metabolic adaptation from long-term low intake is real; after dropping from 145 kg to 75 kg my daily burn fell by about half so that 1600-1800 kcal was enough to stall further loss for the next three years. As far as I know that adaptation happens slowly and isn't easily reversed. I would have expected any extra calories to be used to protect fat stores rather than raise metabolism enough to cause more loss. Clearly your system responds differently.

SharpHarbour92archiveJun 18

Yeah, it's honestly the strangest thing to me. At 3 mg my appetite stayed down, I kept lowering calories, and loss stopped. Then at 6 mg hunger returned, I ate more, and the scale started moving again and even picked up speed. We'll see what happens next. I'm just excited about it and curious whether anyone else has had the same experience. Triz has been amazing overall. Before starting I would crash if I didn't eat constantly, I always needed food, and skipping a meal gave me headaches, brain fog, tiredness, and irritability. Once I began taking it all of that disappeared. It also improved my mental state and reduced thoughts like feeling like a failure. Another odd change is that I had toenail fungus on one nail for a long time; about two months after starting the nail fell off and the new one is growing in healthy. I think these medications can do a lot more than we realize.

Related discussions

Add your experience

If you have tried it, this topic is still open. Sign in to reply — it takes a minute.