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CJC-1295/Ipamorelin appears to be boosting my metabolism noticeably

8 replies6 peopleApr 19, 2026β˜† Follow
Summary

Can CJC-1295/Ipamorelin raise resting energy use enough to stop weight gain on a high-calorie diet?

One user reports taking 500 mcg each of CJC and Ipamorelin daily while eating 2600 kcal yet staying at 259 lb despite expecting gain after years of lower intake. Others flag the original dose as likely a typo and note typical amounts are 250-500 mcg. One long-time user saw only flushing from a standard cycle and recommends HGH for older people instead. No bloating was reported after the dose correction, only a brief hot flash.

What this discussion establishesWhere people disagree

Whether the peptides deliver meaningful benefits beyond a flush for most users

Still open

Long-term results or effects on someone with Hashimoto's and low testosterone

Nothing here is advice.

8 replies Β· 6 people
KeenKettle50archiveopening postApr 19

Been using CJC and Ipamorelin together at 500 mcg each once a day. Feels like it's really lifting my resting calorie burn. Sitting at 259 lb right now and following a 2600 kcal plan with 230 g protein, 340 g carbs and 40 g fat from my trainer. That's far more food than I've managed the past few years while dealing with Hashimoto's and low testosterone, so I figured the scale would move up but it hasn't.

LevelThistle44archiveApr 19

Not sure on all the details but 40 g of fat a day looks pretty low at that body weight. 5 mg of each compound daily would be about ten times a normal large dose. Maybe a decimal got missed?

BrightBeacon35archiveApr 19

Most people seem to pin in the 250-500 mcg range. 5 mg is a lot. Curious how this goes, keep updating us.

SlowSignal37archiveApr 19

Looking at cjc/ipa now that I'm close to my goal and feel like I've lost all my muscle. Has it left you feeling bloated at all?

PatientFenwick91archiveApr 19

Ran 200 mcg of cjc no dac plus ipa twice a day for a full cycle. Only thing I noticed was the flush and that felt decent in cold weather. Takeaway was that if you're older you might as well just use HGH.

KeenKettle50archiveApr 19

Sorry everyone, meant to say 500 mcg not 5 mg. My bad.

KeenKettle50archiveApr 19
↳ replying to @SlowSignal37

Haven't noticed any bloating at all. Just a fast hot flash and nothing else so far.

SlowSignal37archiveApr 19
↳ replying to @KeenKettle50

Was actually concerned there for a minute. πŸ˜‚

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