The ongoing combination of both is more widespread than you might think. I'm doing it myself and there are others here too. Pre-mixed versions give less dosing control and no flexibility. Even though they overlap, they're different with distinct effects and side effects. Appetite control varies, and individual tolerance to sides influences choices. My approach is to get the triple agonist benefits from Reta but keep doses low. At low doses Reta doesn't suppress appetite much, so I add a bit of Tirz for that strong effect. Together they give me full control over eating and eliminate unwanted cravings for bad foods, drinks, etc.
Lately I've noticed single vials that combine Tirzepatide at 20mg with Retatrutide at 40mg from various places. I'm not planning to use that myself, but I'd like to hear about personal experiences with combining them. From what I've looked into, it seems like mixing should be short-term only while switching from one to the other during titration, though that's all based on stories. What are your thoughts? Also, I've come across mentions of micro-dosing both at the same time, which strikes me as excessive for long-term use since they overlap in effects.