How high are folks going with Reta?

Started at 308 and hit 215 this morning. Titrated up gradually over that time. On 10 mg for about five weeks now and not sure about going higher. Doses are split. Might consider adding a small amount of cag.

Built up to 10 mg and held there for roughly five months. Hit a plateau, moved to 12 mg for a month to break through, then reached goals back at 10 mg. Maintaining since then on 6 mg, sometimes 8 mg.

11 mg every six days, which comes out a bit above 12 mg weekly, worked well. Adding tirz on top really helped push past goals quickly.

10 mg works for me, 12 mg for my wife. Recently dropped her back to 10 mg and added 2.5 mg of Tirz. Didn't need to go higher myself since two weight goals were hit. On 6 or 8 mg for a while now.

About five weeks at 0.5 mg, four weeks at 1 mg, three weeks at 1.5 mg, and two weeks at 2 mg so far. Still losing, so no need to speed up the increases.

9 mg every seven days for the past month. Hope to stay here for a bit but tempted to move to 10 mg to finish vials evenly.

On 24 mg a week of Reta, 5 mg Tirz, and 2 mg of Elora. Mostly for fun since I'm within 10 lb of maintenance or at least the end of the cut. Life is good.

24 mg of Reta seems like the most I’ve come across so far. What made you go with that amount?

I take 6 mg every three days, which comes out to roughly 14-15 mg each week.

I’m at 5 mg now and it finally feels like it’s kicking in. I dropped 2 kg over the last week. I’ll watch how the next couple of weeks go and move up only if the loss stalls again. I’m not concerned about needing higher amounts later. I’m down 28 kg total with 23 kg left to go.

I worked my way from 0.5 mg up to 4 mg, splitting it as 2 mg twice a week starting last December. So far I’ve lost 30 lbs and only need 5 more to reach my goal weight. I’m moving back down to 3.5 mg split the same way because I had some nausea last week.

I’ve slowly raised my dose from 5 or 6 mg up to 8.4 mg a week by taking 2.4 mg every two days. I stay cautious with any increase to keep the skin sensations and pain under control. I’m also on 15 mg of tirz and 0.75 mg of cagri while trying to hold onto a 56 % weight loss.

I stayed at 7.5 mg from August until I bumped it to 8 mg after things slowed in October, and that got the scale moving again. I’m keeping any further steps small. If I ever had to go past 12 mg the missing trial data wouldn’t be the only factor; it would depend on where I am in the process and what sides I’m seeing.

My take is the dose is there to handle appetite suppression while weight loss itself comes from a calorie deficit. If the scale isn’t moving there are a few usual reasons: your maintenance calories are lower than you think, either from a miscalculation or from the drop in weight itself; you’re not logging every single thing you eat; or the deficit is so large the body has slowed down. I’d check those first before raising the dose, provided appetite control is already good.

First off, congrats on the progress you’ve made so far. It’s almost twice what I’ve lost and you started after me. Give yourself credit for that. Plateaus show up with anything and sometimes a small change helps. If food noise or appetite is still there, have you considered adding tirz? Hope you reach your goal soon and figure out what keeps working.

I added elora to my maintenance routine recently and it does seem to work as expected. I had a vial tested and the results came back as they should.

That’s some honest math right there. 😅

Been on it 12 weeks and lost 18 pounds so far. Started at 2mg but that gave me bad side effects right away. Went down to 1mg and that worked fine for 6 weeks until progress stopped. Now at 1.5mg and still losing steadily with no issues. Only 8 pounds left to reach my goal but might go a little higher to get more of the glucagon and liver effects since I used to binge drink.