Just curious about results with Reta after being on TIRZ for a year

Thanks. I began at 135 kg on tirz, reached 110 kg, then switched to reta and have lost another 15 kg over seven months. I'll try stepping up every two weeks by 0.5 or 1 mg. Planning to keep tesa for three more months while aiming for another 20 kg by December.

Typical reta steps are 2/4/8/10/12 mg every three weeks or so. Your current pace is slower than that. Losing 20 kg in four months would need faster and higher dosing; 8 mg is often effective. Adding tesa early isn't ideal because it doesn't drive much overall loss and is better saved for stubborn visceral fat once the main weight is gone.

I was on 5 mg tirz. Food interest dropped so much it felt like a chore and progress stalled, so I took two months off before trying reta.

I'll try increasing by 2 mg each month and watch how I tolerate it. Some people do well on low doses, but maybe I'm not one of them. I've also raised weights and protein, so we'll see how it goes.

Thanks. I'll keep raising the weekly dose and see where it lands. I probably haven't reached the right level yet. Even 5 mg tirz felt strong, but that hasn't happened with reta so far.

As a physician I was urged by the rep to increase tirz but stopped at 5 mg because of side effects. After a two-month break I tried reta instead. Many of my diabetic patients lose steadily on tirz over two or three years. Reta has been slower for me and I may not have found the right dose yet. Time isn't pressing and my labs look good, so I'll continue raising it gradually to avoid loose skin.

It's not about comparing with others; everyone has their own metabolic profile. With reta I likely need more than 4 mg. I've been on tesa for two weeks and will check measurements at one month to decide whether to continue eight weeks or stop. The process goes on.