PatientHarbour61

archive participant · first seen Mar 2, 2026 · last active Aug 16
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Gastroparesis
I figure this version has zero influence on ghrelin since it copies growth hormone releasing hormone. A receptor agonist is what fits the n…
Aug 16
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Tirz experience = Reta experience?
Switching abruptly from a high amount of the first medication straight into the lowest starting level of the second one feels really ineffi…
Aug 16
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What tipped the scale for you in your decision to stack your GLP with another or add in an amylin?
I started with twelve during the first week then went to eighteen the week after that and twenty four after. Side effects have never shown …
Aug 14
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Gastroparesis
Compounds of that type saw clinical testing regarding stomach emptying issues in diabetes cases. A certain version got developed specifical…
Aug 13
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Switching from Reta to other (generic) GLP-1R agonist
Almost every complaint online about reta not working comes from people switching from high-dose tirz. For some reason that switch often doe…
Aug 12
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Switching from Reta to other (generic) GLP-1R agonist
The top reason people dropped out of the phase 3 reta trials was losing too much weight at the dose they were given.
Aug 12
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Tirz experience = Reta experience?
I'd probably avoid reta with BP that low. It could cause symptomatic hypotension, at least orthostatic. Your BP probably won't fall much mo…
Aug 10
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Tirz experience = Reta experience?
If you're in the trials or the expanded access program and getting it from Lilly, that would count as brand name. The drug itself still doe…
Aug 9
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What tipped the scale for you in your decision to stack your GLP with another or add in an amylin?
I'm less optimistic about DEXA accuracy. I've seen results showing very low body-fat percentages after major weight loss that don't match v…
Aug 6
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What tipped the scale for you in your decision to stack your GLP with another or add in an amylin?
I had been maintaining on 12 mg reta, but after starting a steroid cycle that became unworkable and I was eating well over target on many d…
Aug 5
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FDA compounding approvals!!
That's the reason they create a patentable version, like the dropped MOTS-c analog CB-4211 or the approved tesamorelin. Extra credit when i…
Aug 3
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Evolving personal weight loss goals and when to stop
With five kids you could get some nice progressive overload just switching between them. Start with the toddler press and work up to the th…
Jul 20
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Evolving personal weight loss goals and when to stop
Current number in my head is 170 but unsure where I'll actually land. Don't think I'll get there and that's okay. At some point I'll run ou…
Jul 20
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Study: Do Fasting GLP-1 and GIP Levels Predict the Initial Pharmacological Response to Semaglutide and Tirzepatide?
I have a guess about why that disappointing outcome showed up. Using just one of those medications probably isn't something that stands apa…
Jul 16
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Study: Do Fasting GLP-1 and GIP Levels Predict the Initial Pharmacological Response to Semaglutide and Tirzepatide?
I came up with a better graph than the last one we looked at.
Jul 16
started a topic
Study: Do Fasting GLP-1 and GIP Levels Predict the Initial Pharmacological Response to Semaglutide and Tirzepatide?
I came across research exploring if initial fasting measurements for GLP-1 and GIP could indicate how individuals might respond to those tw…
Jul 16
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Legal issues
The main manufacturer isn't really losing money on the gray market yet. Their prices still target insurers and employers rather than indivi…
Jul 15
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Is Losing Weight Too Fast Actually Bad?
The metabolic slowdown seems tied to large total loss rather than speed alone. Their method of predicting expected RMR from DEXA scans may …
Jul 7
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Need to cut back on supplements
NAC supports glutathione production, not NAD.
Jul 6
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Tirzepatide vs semaglutide vs retatrutide: starting choice, sides, and escalation
It seems like the way most people first run into this involves virtual clinics along with pharmacies that prepare their own batches, beginn…
Jul 6
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