Calories and nutrition: Before retatrutide I would swing intake from 1800 a day on the low end to 3500 on the high end when moving from cut to bulk. Staying under 1800 felt unsustainable and anything over 3000 tended to add fat quickly once weight climbed past 300 lb. Currently at 2.5 mg per week intake sits at 1400-1500 daily with a steady 1.5 lb loss per week that feels almost effortless. Once a logical level of leanness is reached, probably mid to late 2026 given the slow pace, it will be interesting to see how retatrutide affects nutrient partitioning during a bulk thanks to GIP agonism favoring glycogen replenishment and thus needing less surplus. Protein and fiber remain the main targets; protein is inefficient for the body to convert into fat since it must first become glucose.
I've been thinking about pairing peptide protocols with particular training blocks to maximize results. This is purely a thought exercise since multiple protocols could run together, but if choosing one path here is how it might look. I'm interested in others' experiences with similar long-term goals like staying strong enough at 80 to lift grandkids. Peptide protocols: 1. Cellular health and repair over 18 weeks. A 14-week outline exists for running SS-31 then MOTS-C with NAD+ the whole time. Because SS-31 focuses on mitochondrial repair and MOTS-C on AMPK activation, it might fit to extend with an 8-week addition of SLU-PP-332 at the end while keeping NAD+ to promote mitochondrial division. Fix the cell, power it up, then increase the number. 2. Growth/recovery protoc