Switched from tirz to Reta then back to tirz

Stalls always end for me no matter what. Stacking different ones in the same week works, as does moving up faster or splitting doses or switching to every other day. Those approaches have all paid off eventually.

You dropped weight on tirz, tried reta next, then paused everything and regained around twenty pounds, which is typical when stopping. Going off and restarting these meds often makes them work less well the next time, based on what people report and one study. Maybe the current amount is not high enough to match that reduced response.

From an earlier post by the original poster before the switch to reta, continuing with tirz would mean stacking. Some reach twenty plus milligrams successfully, though returns may be smaller than with stacking. Trying cagri once before was mentioned, and elora is noted as a newer but more expensive option.

Use the loseit app, set it for sedentary activity, log every item, and skip adding back exercise calories.

A recent thread covers similar ground with ideas like trying reta, adding cardio, or accepting the plateau. One person started compounded tirz last Thanksgiving at 245 and reached 181 but has stayed there for four weeks after an earlier stall at 187.

When I hit a stall at a dose I switch to every six days instead of seven and can usually continue losing for another eight to twelve weeks without raising it. Eating more for a couple days also helps when restriction has been too tight; a refeed gets things moving again for me.

Curious how rough the tiredness gets for most folks on tirz. Thinking about adding it to reta but really don't want to feel wiped out all the time and leaning on energy drinks nonstop.

One way to look at the tiredness is it's your body doing some healing on top of the lower calories and getting used to the GLP plus its stomach effects. Either way adding tirz to reta tends to work like adding it to sema, giving a nice lift if the sides stay manageable.

Only three weeks back on means it's still early, and the first month often shows scale shifts from water and glycogen either direction so don't read much into it yet. Putting weight back on after stopping or switching is pretty typical, so it doesn't mean anything's wrong on your end. Honest tracking for a bit plus keeping protein high will give clearer info than looking for new stacks, and check any dose tweaks with the prescriber. It's the usual boring advice but sticking with it tends to pay off.