This issue popped up for me with one version and for my spouse with the other. We found that inserting a longer needle into the upper arm area avoided part of the body's defense reaction. Wiping the spot with a certain spray both right before and right after the shot also helped. Moving to another version usually clears it up without fail though it is not the first choice. Folks who keep going through it often notice the problem fades after a couple months once it shows up. If the response spreads and causes welts in spots away from where the shot went in then switching versions is what we did.
I've been on this medication since May of last year. Family members using identical batches have had zero issues. Starting in August I developed itchy welts that grow from quarter size up to half a tennis ball and stick around roughly three days. Stomach injections with spacing still led to worsening reactions and the same thing happened in my thigh. I assumed it was fat buildup until the thigh swelled despite no injections there for a month. This feels like an allergy. Has anyone else run into it and should I consider a different source or switch to tirzepatide?