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Better heat tolerance on GLP meds?

34 replies20 peopleJul 2, 2026☆ Follow
Summary

Does taking GLP-1 drugs improve tolerance to hot humid weather?

Users report handling heat and humidity better after starting GLP-1s, with examples of jogging or working outside without previous discomfort. Most attribute the change to weight loss rather than a direct drug effect, though a few note feeling generally colder overall. Sweating patterns also shift for some, either increasing or decreasing. Experiences vary by location and how much weight was lost.

What this discussion establishesWhere people disagree

Whether the benefit comes from the GLP-1 itself or simply from carrying less weight

Still open

Exact contribution of the medication versus weight loss or lifestyle changes

Nothing here is advice.

34 replies · 20 people
PatientPebble33archiveopening postJul 2

Anyone else finding they handle hot humid conditions better while taking GLP meds? I'm on Ozempic now and used to really dislike that kind of weather, but it doesn't affect me anymore. Yesterday it hit 32 Celsius in Toronto and I went jogging without any problems at all. Same question for people on sema, tirz or reta?

ClearQuill84archiveJul 2
↳ replying to @PatientPebble33 (opening post)

Yeah, but I think it comes from being slimmer rather than the drug on its own.

BlueAlder28archiveJul 2
↳ replying to @PatientPebble33 (opening post)

Absolutely. Last summer my bedroom at 78 degrees at night made sleep miserable before Tirz. Now I even use covers at similar temps. Like others said, it is probably more about the weight loss than the meds. On the other side, I was freezing in March when the office was 62 degrees and considered heated vests until the rapid loss made sizing pointless. I used to enjoy daytime 60s and bedroom 50s, but that will cost me this winter.

PatientPebble33archiveJul 2
↳ replying to @ClearQuill84

Except I have only dropped 7 pounds so far, from 206 down to 199, with another 25 still to go. Maybe even a small loss makes a noticeable difference though.

AmberCinder18archiveJul 2

Here in Bama dealing with 100-plus temps, I need a lot more activity before I start sweating when working outside. Still not sure if the med or the 40-plus pounds I am no longer carrying is the reason.

SlowBramble67archiveJul 2
↳ replying to @PatientPebble33 (opening post)

Yeah, that's accurate. A year ago during summer I'd be dripping sweat just sitting still in the shade when it was warm. Recently here in Belgium the heat hit 41 degrees Celsius yet it didn't bother me much. My weight dropped from 102 kilograms down to 74, my cholesterol levels went from 195 to 161, and blood glucose from 98 to 77. The improved heat tolerance comes from all that thanks to the GLP-1 medications.

PatientPebble33archiveJul 2
↳ replying to @AmberCinder18

I noticed the same thing. I am sweating more now, but that is fine as long as the heat and humidity do not feel suffocating.

NorthWillow72archiveJul 2
↳ replying to @PatientPebble33 (opening post)

I got much colder once the pounds started coming off and I sweat less now too. Not sure how much came from the weight loss, being more active, or eating cleaner. Either way I am glad I no longer have to wring out my shirt in this Texas heat.

PlainAlder11archiveJul 2
↳ replying to @NorthWillow72

My wife and I both notice it. I raised the AC to 78 degrees a while back. Neighbors get annoyed when I do yard work in the afternoon without sweating. We have lived in Florida forever so we are used to it, but it is still hot as hell.

LevelThistle44archiveJul 2

I work outside in Mississippi but spend most time in air-conditioned equipment now. Last summer was okay, but this one feels better after losing 70 pounds. A couple days ago the heat index hit 110 F or 43 C. At home I have moved from sleeping at 68 degrees to 72-74, which turned out to be a nice surprise.

SlowLedger31archiveJul 2

Reta while in a deficit definitely makes me cold. I used to be the kid running around half naked, but now I wear socks around the house.

CopperLantern66archiveJul 2

It is definitely noticeable, though I am not sure if it is the weight loss or the med itself. I have lived in AZ my whole life and this is one of the first summers I can recall where the heat has not felt unbearable already.

WarmCompass27archiveJul 2

It sounds more tied to body fat percentage than the GLP-1s. My hyperhidrosis improved a lot after losing weight. I used to feel sweat dripping from my armpits the second I entered a heated room, and moving from cold to warm was the worst. Even without GLP-1s the symptoms eased as weight came off. During the NYC heat wave a casual walk produced no sweating. I also feel colder now at my current weight than I did at the same weight two years ago, pointing to body fat or lean mass as the factor.

PatientPebble33archiveJul 3
↳ replying to @ClearMeadow14

Yesterday I compared the temperatures reported for Toronto as well as New Orleans and Toronto registered two degrees Celsius warmer.

PlainAlder11archiveJul 3
↳ replying to @PatientPebble33

That is not normal for you guys. We deal with this crap from June through October and sometimes longer. It is considered subtropical where I live in SW Florida.

PatientPebble33archiveJul 3
↳ replying to @PlainAlder11

It is not. We are having a bit of a heatwave right now. Toronto fire reports showed a surge in heat-related emergency calls and some city pools stayed open late. The heat wave kept going across the Greater Toronto Area and the rest of Ontario.

PlainAlder11archiveJul 3
↳ replying to @PatientPebble33

I saw all that on the news this morning. The whole upper east side of North America is dealing with it. We are probably more equipped for the heat here, but you handle cold better.

GreenPebble54archiveJul 3
↳ replying to @PlainAlder11

Yeah, SE Florida here. It is hot and humid more often than not. On the original point, I also handle heat better now on tirz and chalk it up to lower weight and fat.

NorthWillow72archiveJul 3

Being from the gulf coast area, extreme temperatures and moisture don't surprise me much, yet we've got ways to handle them. My cooling setup adds up to seven tons across a couple of systems. Places lacking whole-house climate control are facing real trouble, and that kind of setup couldn't handle conditions around here. The wet bulb reading shows more about what's actually going on, plus regions along the eastern side and up north are dealing with tough conditions during these months. Even Toronto is nearly matching the discomfort levels we see down here at the moment.

RustLantern55archiveJul 3

I feel like I tolerate heat pretty well in general but sweat a ton when active in it. That is normal but still seems like a lot. I played softball last night with a heat index of 106 F when we started and ended up drenched. Everyone was dripping. I felt pretty bad by the end but we played two games and scored 24 runs in the second so I had more at bats than usual. I am close to goal weight. I also notice I get colder than others around me and am not used to carrying a jacket, so I get cold in church or stores.

SlowSparrow49archiveJul 3

I didn't catch that exact detail, yet overall both my partner and I tend to feel more chill while on these meds, so we raised the house thermostat. It looks fairly common from reports I've come across, which suggests a link. Greater cold sensitivity shifts your comfort range higher, meaning warmer conditions no longer bother you as quickly. For instance what once felt fine at lower settings now needs even higher ones before discomfort starts.

PatientPebble33archiveJul 3

Okay, so today was 36 Celsius and that was too much. I had to seek shelter during a jog. 32 Celsius I can handle, but 36 is too much. Those four degrees make quite a difference.

PlainAlder11archiveJul 3
↳ replying to @SlowSparrow49

Same here. We have gone from 77 degrees inside to 79 now. We also carry long sleeve shirts in the truck in case we stop somewhere that keeps it in the low 70s. It is the Reta I am sure.

SharpCinder28archiveJul 4

Summer heat pairs perfectly with these meds because I can sip strawberry lemonade and skip any bad feelings afterward. Earlier I noticed several stands selling the drink run by kids with their families.

SteadyQuill55archiveJul 4

I started on GLP-1s last June at 176 pounds and noticed my heat tolerance went way down. I was bummed because of Texas. But at 126 pounds the heat barely seems to affect me, even if I do sweat it stops as soon as there is a breeze.

SharpCinder28archiveJul 4
↳ replying to @SteadyQuill55

The wind feels like it's blowing warm air from a machine, funny enough. I've built up more resistance to high temperatures, and I've also been moving around way more these days.

SteadyQuill55archiveJul 4
↳ replying to @SharpCinder28

It is awesome. I live three miles from my job and can ride my bike in without getting drenched when I arrive, even on the one day a week I go to the office.

AmberAlder67archiveJul 4
↳ replying to @PatientPebble33 (opening post)

It appears my capacity for this has increased, and I assumed the thirty pound shed was responsible.

PlainMarble21archiveJul 4

Losses have been pretty small up to now, but the three of us taking this around the place notice the cooling system leaves us chillier than during the previous season, so I raised the temperature setting and our power costs dropped nicely.

PlainAlder11archiveJul 4
↳ replying to @SharpCinder28

That might hold true in your spot. Here though any wind comes across as damp probably from the water content in our air.

AmberTimber37archiveJul 4
↳ replying to @NorthWillow72

Why would readings above eighty degrees ever get colored that intense fiery orange-red? Two decades back the same level showed up in green or blue instead. Only stuff past a hundred got painted red. The body runs close to ninety nine anyway.

NorthWillow72archiveJul 4
↳ replying to @AmberTimber37

We're talking about the wet-bulb reading here. Issues kick in once that measure hits between twenty-six and thirty degrees Celsius, or roughly seventy-nine to eighty-six Fahrenheit, since the system can't shed heat the usual way. Past thirty-five Celsius with total moisture saturation, lasting beyond a couple hours without machine assistance simply isn't feasible.

AmberTimber37archiveJul 5
↳ replying to @NorthWillow72

People should know that 95 F and 100 percent humidity is theoretically possible but exceptionally rare and unsustainable in open atmosphere. As a pilot I regularly joke that it is 93 F outside and 100 percent humidity, but of course it is not. Wet bulb temperatures approaching that level are beyond dangerous. Typically here in South Florida when we see 93 F we see humidity in the 70 percent range with higher fleeting peaks.

PatientPebble33archiveJul 5
↳ replying to @NorthWillow72

FYI France and Paraguay played their World Cup match today for two hours in Philadelphia at 37 C. I am amazed nobody dropped dead.

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