I had my growth factor levels checked recently to establish a starting point, though the numbers haven't arrived. I began the sermorelin and ipamorelin combo that evening and plan to get a supply of tesamorelin soon. I'll likely continue with the sermorelin for a month or two until it's finished, check the levels once more, and then switch over to trying tesamorelin. When do you usually inject, morning or evening? I'm aware evening works better, yet your outcomes are impressive enough to make me wonder.
Tesamorelin dosing schedules stacking side effects and fasting optimization
206 replies · 81 people · page 4 of 5
↳ replying to @SlowFenwick25
I handled it early in the day to confirm my body had no food. A few folks mention evening timing might support better rest though.
I can't figure out why people skip the 4mm pins. They don't hurt and give only minor isr.
↳ replying to @SlowFenwick25
I've come across quite a few measurements of igf1 levels involving tesa alone or paired with ipa, and also cjc combined with ipa, yet nothing on serm together with ipa, which makes me interested to find out. Among those options, serm possesses the briefest duration in the system and is likely to produce the smallest rise in igf when following common approaches, though adding ipa ought to provide some benefit.
Here's one more experience. Over a period of two months I took reta while doing weight training three times each week without fail. The sessions grew harder over time so I had to lower the weights to get through my repetitions. Adding extra carbs ahead of training sessions made no difference. I lost around three to five percent in strength on all my exercises. After that I started CJC/IPA at zero point three milligrams nightly on work days. This didn't yield any improvement after a few weeks. I then tried taking it in the morning sixty minutes before consuming anything and felt a change after just several days. Weights started going up again each week and I saw solid progress during the next month as I continued dropping body weight. I stopped for two weeks during a holiday. A buddy had issues with Tesa so passed me his ten milligram kit. I used one milligram on mornings of weekdays. Recovery and strength improvements might even be greater than with CJC/IPA and my tracked deep sleep time went up. Lately I'm able to increase loads every time I train. I'll test my IGF-1 levels in a couple weeks. On a separate note I've used fifty milligrams per week of TRT for a long time which keeps my total around five hundred and the doctor thinks that's okay.
I've been using these two compounds together. Started the first one about four weeks ago. My fifth injection happened the day before, following a gradual increase: half a milligram twice, then a full milligram twice, and one and a half yesterday, with plans to hold at two for some time. For the second compound, I'm on day twelve at one milligram nightly, taken fasting roughly sixty minutes prior to sleep. It's premature to judge results much because the timelines overlap so closely, yet my rest has improved noticeably. I have supply lasting two months, so I'll check in around the sixth or seventh week on whether to keep going. That choice hinges solely on any adverse reactions, of which I've seen none yet. Should I proceed, I'm undecided between staying at the current level or increasing to two milligrams. Shedding belly fat is a strong goal for me, though my limited budget restricts options.
↳ replying to @KeenMeadow61
My initial reading showed one hundred twenty on igf-1 with a z-score of negative four tenths. Six days have passed since I started the serm and ipa. Results remain to be seen.
Wondering when things might shift, buddy. The reading on my scale keeps rising even though I've cut calories hard while using three milligrams.
↳ replying to @BlueWillow20
After about six weeks where my weight kept rising the water retention finally ended so the scale started dropping.
↳ replying to @ClearKettle18
Cool. Are you seeing any fat come off?
My spouse will probably begin using it in the next few days. We had thought two milligrams would be the starting amount but the replies here make one look like a better option. Any benefits or drawbacks if we try that approach for the first week?
I'm trying to work out the proper quantity for this Tesa and IPA combination product. A 9 to 4.3 ratio version is up for sale and I've been looking at it, but I'm completely unsure about the initial steps for dissolving it or calculating how much to take each time.
Normally I never recall dreaming at all. Lately this substance has flipped that around completely. I give myself one milligram right at three in the morning before starting my first delivery shift. That leaves an extra couple hours of rest while containers get emptied at the hub. Those hours turn into long stretches of intense, wildly odd dreams that stay crystal clear once I open my eyes.
A recent one took place at the facility near the German border that still has an old wartime shelter on the grounds. Friendly soldiers from that era were offering me a hot drink inside the shelter. The usual two loading bays suddenly became more than twenty, and I couldn't spot my own rig anywhere. One soldier pointed me toward a black vehicle even though mine is yellow. I climbed in, the engine fired right up with my key, but the cabin looked completely wrong inside. That mismatch made me understand I was dreaming, and then loud knocks on the door yanked me awake. A worker outside said unloading had finished. I spent the rest of the day grinning at the whole thing.
Fresh bizarre stories show up every single time I follow this pattern. They never appear during regular nighttime sleep, only after the morning dose, so the link seems obvious. These nightly adventures feel so good that I expect to stick with it for years.
Man that expense for sema really stings though. I went through the exact same process with tirz. There's no telling how it feels until you've tried it yourself. 🤷♂️🤷♂️
↳ replying to @SlowBramble67
It's impressive how clearly you remember that dream. Back when I tried those patches while stopping smoking, my dreams turned super vivid and stuck in my mind afterward. I even started looking forward to bedtime just for the scenes playing out while I slept. Sadly my current stuff doesn't seem to touch my dreams at all, and I wake up with no recollection whatsoever.
For the past three months I've taken two point five milligrams of that compound each morning on an empty stomach. Haven't noticed any unwanted effects or injection site reactions either. Yet I can't point to any real drop in weight from it alone since I've also been using another one starting at the end of March at two point two five milligrams two times weekly. Studies from back then with patients who had HIV indicated roughly fifteen percent less belly fat after half a year on average. That doesn't seem like much change if someone had ten pounds of it to begin with they'd only lose about one point five pounds following six months of daily shots with what costs the most among these assuming the results match the typical case. Saw a talk by some online personality recommending to skip this and go for a mix of two others instead. Some others online call it very strong but for me it's just average at best.
↳ replying to @GreyPebble34
The process begins right at purchase time. As an example I got twenty milligrams of one item plus ten milligrams of the other. After that I mix them using a one to zero point five proportion. Getting the pre combined version shifts things to a one to zero point three proportion from what I remember.
↳ replying to @RustBramble70
It's unlikely those will lead to shedding pounds. The growth one tends to increase appetite. It also causes the body to retain fluid even as it reduces internal fat. I do drop a bit of weight when combining them, yet the deficit in calories along with exercise is what drives it. Besides, I'm not someone who drinks a lot. Just a few mugs of plain coffee and no more than that amount of fluid daily, which falls short of guidelines, though I don't try to limit myself on purpose, I simply have no desire for more.
I like how this performs yet avoid buying large quantities upfront. Sensitivity to MOTS-C may lead to responding to Tesa over time as well. The reaction stays milder and tolerable though still bothersome.
↳ replying to @SteadyCinder74
After my morning injection how much time needs to pass until I can have a meal?
↳ replying to @ClearAnchor49
People claim there's no reason to delay consumption because that early study showed solid reduction in abdominal fat even without changing meals. Still, since insulin might impact how these growth hormone releasers function, it could be better to take them without food in your system. I typically hold off for sixty minutes prior to a meal, though I'm not certain it matters. Lots of folks who skipped the waiting period still saw solid increases in their growth factor levels. Honestly, I begin sipping plain coffee right after the injection, and the stimulant might lessen results through elevated stress hormone.🤷
↳ replying to @SteadyCinder62
This situation is becoming extremely bothersome, leading me to seriously contemplate changing over to human growth hormone instead. Every time I try to inject, I end up with a swelling or bump that keeps me scratching for three to four days straight.
↳ replying to @AmberSignal37
Hexarelin turned out well for me because it caused neither side effects nor any injection site reactions.
Right now my routine includes two milligrams of reta every seven days, one milligram of SS31 on weekdays, two milligrams of MotsC on three days each week, plus one milligram of tesa on weekdays at night. When I wake each morning I find myself able to recall what I dreamed. No negative reactions so far and everything feels fine. This is my third week and I intend to continue the same way. At this point I am thinking about raising the reta amount to three milligrams since appetite has gone up, though I cannot tell whether that comes from tesa or the other two compounds. Adding NAD+ might happen too, yet the number of injections already seems high.
↳ replying to @AmberSignal37
Yeah, that's probably wise. I should review those lab reports shared by the group. It might turn out a certain production run has unwanted materials setting off the reaction.
↳ replying to @AmberSignal37
After changing over to growth hormone instead of those peptides I noticed clear improvements overall. The odd reactions such as skin redness stopped happening and injections no longer need any planning around food times. My score moved up from negative point two on the earlier mix to one point two now. Both compounds increased my appetite compared to using nothing. Raising the weekly dose by one milligram got the scale moving downward once more. Right now I'm under my target body mass and just five pounds short of my personal record low from adulthood.
↳ replying to @AmberMeadow80
Was the change due to those problems? Which dosage level are you on now? The effects from my mix have been great in other ways. Bone score went up from 0.2 to 1.7 with the two milligram amount. Losing fat, bouncing back faster, and getting stronger has all been amazing. Still, those itchy bumps that stick around for days seem off, turning each shot into a hassle. I also dislike having to schedule it precisely. Evening would be better for me, yet late meals mean I worry two hours won't suffice, so I end up with it early in the day. Morning isn't bad except needing to sneak it while my young kid needs my focus. On top of that, once I stopped the previous med, this one makes me super hungry all the time.
↳ replying to @SteadyCinder62
My sample came back spotless after every check. Plenty of users notice the same effect from this compound. Official studies on the pharmaceutical version mentioned it repeatedly too. The usual explanation points to the body mounting a defense.
↳ replying to @SharpCinder28
Any issues pop up for you with Tesa? Honestly I'm probably not switching over to a new secretagogue after this. GH looks like the move coming up next.
↳ replying to @AmberSignal37
I don't know what my baseline igf-1 level or z score would be naturally. A -0.2 z score from twice daily cjc/ipa shots didn't seem very effective to me. Maybe the weak result came from slower digestion caused by reta or perhaps my age in the early fifties. That led me to try GH instead. Right now I'm using 3iu of GH each day. I plan to raise it to 4iu after checking fresh blood results and handling any side effects. I've been dealing with some pain in my elbow from golf. People in similar situations have reported elbow troubles while on GH. Since I climb rocks, I've dealt with this elbow issue previously due to repeated strain. I need to figure out the cause before raising the dose.
↳ replying to @AmberMeadow80
Both elbows feel sore with what looks like golfer's elbow, and the cause appears to be the curls I do when working out. Not long ago I sprained my wrist in the TFCC area by swinging a bat, at a time when I also had swelling in the wrist from fluid buildup while on Tesa. I wondered whether the extra fluid made the injury occur more readily. I also questioned if the soreness lately connects to Tesa or if it's unrelated. Has anyone noticed cases of golfer's elbow appearing alongside growth hormone use or elevated IGF-1 levels?
↳ replying to @LevelSignal72
Due to everything I've absorbed from discussions lately, I'm uncertain about the origin of that info. Could have been a specific person or site. Can't really tell.
↳ replying to @AmberMeadow80
Has the switch worked out well for others? The peptides gave me really good effects, though the places I shoot are causing me a lot of trouble. That's why I'm considering the switch to growth hormone. Being a forty year old guy, I wonder if I jumped in too soon. My baseline igf sat around 157 before, and after the two milligram amount it reached 294, plus nice changes in losing fat and recovering faster.
↳ replying to @AmberSignal37
Absolutely. My rest has been fantastic and I rebound well after workouts. Being in my fifties this supports reaching some fitness targets.
After getting a kit with those two things I went ahead and checked my starting levels first. The reading came back at 202 for IGF1 along with a z-score of 0.8. Now I'm leaning toward skipping the whole thing.
↳ replying to @GreenThistle62
As a thirty six year old guy my starting IGF number sat at one hundred sixty nine with a z score of zero point four. Two milligrams pushed it as high as five hundred IGF and a three point zero z score. I dropped down to one milligram and landed at three hundred thirty IGF with a two point zero z score. Amounts like one milligram or half that much look like they would land between one point five and two point zero z score.
↳ replying to @LevelSignal72
Might start at half a milligram after all. The kit is already bought. 😂 40 year old male
↳ replying to @AmberMeadow80
Good to know. If I were in my fifties there would be no hesitation. I just didn't want to start too soon. I really wish the injection reactions from Tesa weren't happening.
I wish someone had pointed out that Tesamorelin gets ruined by freezing. That turned into an expensive error on my end. I never came across that detail in my own reading. Explains why results are minimal. At least there are no injection site reactions.
↳ replying to @SteadyTimber22
Are you referring to already mixed tesa?
↳ replying to @SteadyTimber22
The freeze-dried version of tesamorelin does not break down from freezing and belongs in the freezer to last longer.
No, not only the mixed version. A video at the thirty-three minute mark. I get why you wouldn't freeze a liquid solution, but the claim is it applies in every state.
Is that source wrong? Hoping for a clear answer either way. It's still sitting in the freezer with the rest.
The lack of noticeable change comes from GH peptides needing more time to show results than testosterone or the GLP types. Tesa also tends to have milder impact unless IGF-1 started low. Freeze-dried HGH handles freezing fine, and the same holds for tesa. Official guidance against freezing the dry form is mostly regulatory, though there is a small basis. I store my dry peptides in cheap insulated soup containers from a thrift store. Any minor loss of potency is not a real concern.
↳ replying to @LevelSignal72
That is a really helpful reply. My starting point was only ten points behind yours yet I reached 294 IGF on 2 mg. I would love to use just 1 mg and still hit a solid z score.
↳ replying to @SteadyTimber22
You run into those reactions as well?
↳ replying to @SteadyCinder74
Agree. The earlier point is right. I have seen advice against freezing HGH, but the unreconstituted tesa should go in the freezer.
↳ replying to @SharpCinder28
That is interesting. What is the benefit of those soup containers? Keeping out moisture from condensation? I store my dry peptides in zip bags inside the original ten-pack cases, plus desiccant packs and a fresh paper towel that gets swapped every few days. The container idea sounds worth trying.
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