Tirz stopped working? Reta made me hungry. Send help (or snacks 🍕).

Tried adding Cagri to a high Tirz dose earlier and got great appetite control but quit after two shots due to a mild reaction. Hit a long stall and four weeks ago added the lowest dose of Sema, which gave very strong suppression to the point of needing to force calories in. Scale has not moved though. Lowering Tirz a bit this week and raising Sema for the second month. Several others have added Sema successfully during stalls.

Maybe the earlier side effects were not from Tirz after all. With changes every two to three weeks it can take time to reach higher levels again. Suggest staying at 5 mg for four full weeks before going up, and keep hydration high.

The title made me laugh. Depending on what you are using you could just keep raising until something changes. I went up to 9 mg then back to 7 mg with little difference either way and no strong effects at the higher amount.

Check a chart showing blood levels based on half-life, dose amounts, and injection dates. These medications need about five weeks to build up fully and another five to stabilize after any change. After the break your current levels are lower than when you stopped, so more time is needed to reach the same point.

Reta raises my hunger at low doses. The other two options stop it quickly.

Reta gave no weight loss or appetite effect until reaching 6 to 8 mg. Would suggest picking one compound and, if staying with Reta, going higher.

Currently stacking Cagri with Tirz. 5 mg is still low so more titration may be needed for better control. In the meantime focus on protein and lower-calorie choices such as spinach in an omelette.

That amount comes across as pretty mild. Without any unwanted reactions you could move up the levels faster. Up to the top studied amount there's no real concern if everything feels fine. That top amount is considered okay even for frail elderly folks, so someone in good shape shouldn't stress over it.

I promise not to mention anything to your mother. Parents often worry we aren't eating enough. It's great you're nearly at your target, just 15 pounds left. Wisconsin offers some fantastic hearty meals and excellent dairy products, which can complicate controlling hunger. I appreciate the suggestions including the divided amount method. I'm planning to keep the increase gradual for now. Enjoy your day as well. 🫶

Right now my doses are five tirz plus one point five reta and I have no appetite whatsoever.

You're more daring than I am. After terrible side effects lasting days from 4mg I stopped raising my reta dose from a low level. (Definitely earned my spot in the Reta Hall of Shame!) My current maintenance is 1mg every ten to fourteen days together with 1mg tirz. Plenty of people question whether combining the two makes sense, yet the synergy delivers solid results for me.

Plenty of solid points in the thread. Ultimately the only thing that counts is reaching a healthier weight with whatever approach you pick. A single peptide at low dose would be ideal, but reality often complicates that. If stacking becomes necessary you still get my vote to stay safe. I keep wondering whether the next big new option will push Reta aside the same way Tirz got replaced. For anyone dealing with bad GI problems, checking microbiome health can help, especially with the usual sulfur burps that are straightforward to sort out.