Users describe inconsistent results with PT-141 at doses around 1-1.75 mg injected. Some notice stronger and longer-lasting erections with flushing but no added sensitivity, while others feel nothing or experience nausea that ruins the mood. Effects can build slowly and persist for hours, sometimes leading to multiple rounds of activity or overnight issues. A few suggest lower doses or combinations to improve results.
What this discussion establishesWhether PT-141 reliably increases sexual desire versus just physical response, and how well it works without side effects for different people.
Still openBest dosing strategy or timing for consistent results without risks like prolonged erections.
Nothing here is advice.
Mid 40s guy with no sexual function complaints but curious about how PT-141 might feel. Tried 1.75 mg injected under the skin last night roughly three hours before bed and an hour after eating. Nothing happened at all. Listened to music for a while then went to sleep. Curious if others have noticed any benefits or sensations from it.
It worked for me but almost too strongly. Reminded me of the weekend Cialis idea if that marketing were more accurate. Now I stick with smaller amounts like 1 mg.
I thought this was supposed to affect sexual desire rather than sleep. In men it produces erections.
Yeah it is promoted for sexual desire. I chose to take it three hours before bed so I would not be dealing with an erection during the day. Still felt zero change in desire or any physical response.
How long did the effects last and what did it actually feel like if you do not mind sharing.
We will have the house to ourselves starting in the fall. Considering setting aside a day to try PT-141 together even though neither of us has any particular issues. Seems like it could be interesting with all the extra time alone.
Maybe pairing it with oxytocin could make a difference. I have not tried that yet but some information suggests the two can work together. Around Valentine's some sellers offered them as a pair which is how I ended up with both.
Thanks, I will look into that.
My partner and I decided to give it a shot. He was ready to go but I ended up feeling sick and throwing up. Not exactly the mood we were hoping for. Not for me.
That sounds pretty rough. I guess I got off easy with no reaction at all instead of getting sick.
Had the same result at 45. Noticed the usual flushing after about an hour but the planned session did not happen.
The sensations were similar to Viagra or Cialis with no extra sensitivity. What stood out were the spontaneous erections that stayed around for hours at the higher dose. I had to manage it because of worry about lasting damage and it was harder later when sensitivity dropped. The start was very gradual unlike the other two. Starting at 1 mg is safer than adding more later if nothing shows up right away.
Thanks that was really helpful.
Oxytocin seems even more delicate than HGH. The one I recently mixed had particles so I am tossing it even though I used the usual sterile water. Since it was the only one I had I probably will not bother again and will look at natural ways to raise levels instead.
Partner and I both tried 1 mg in the afternoon. Both got strong flushing right away but no other problems. Waited hours for something to happen but it never felt like it kicked in. Eventually went to the bedroom anyway and the experience was much stronger than usual. A couple hours later we were at it again for another hour until exhausted and sore. Woke up more than normal during the night with very strong erections. Had to sit to pee because standing was impossible. Next morning still felt like more would be good and went with it despite the soreness.
Just a note that PT-141 is only approved for certain women at the 1.75 mg dose. For men who respond strongly that amount can be too much and raises the chance of extended erections more than other options. Lower amounts around 1 mg may be better. People who do not respond at first sometimes adjust timing or go up to 2 mg.
It made me feel nauseous but also aroused. Same thing happened to a woman I know who tried it. Worked well once the sick feeling passed.
There is mention of it being used by a postmenopausal woman in her seventies.
If you are going to mention that you should also check what studies were done in men, what issues came up, whether it was tied to how it was given or points to wider risks, and who should pay attention. That history would be useful for anyone thinking about trying it.
The best one I have tried for this purpose is GHB though it can be hard to find.
As noted the 1.75 mg amount is often too high for many men and can increase the chance of extended erections compared to other compounds. That it is approved only for some women at that level makes sense. It might work better alongside something else for a more balanced effect and lower risk. Certain other medications could interact badly with it.
Usually I say I sleep through one of them and that is usually the 4 am one.
One report mentioned a partner moving to another room possibly after a 3 mg dose. Advice in that discussion was to use very small amounts especially if other levels are in range. Other suggestions include certain over the counter options or a cold shower if an erection lasts too long overnight.
That is what happens when someone keeps it all to themselves. Sharing is better. Good info though.
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