Half-lives / PT-141
PT-141 half-life
PT-141 stays in your system about 13.5 hours — five half-lives at a half-life of ≈ 2.7 h (2.7 h). The computed decay curve is below, with the primary source cited.
Also searched as: pt141, bremelanotide, vyleesi.
Source: FDA VYLEESI (bremelanotide) label, NDA 210557 (2019); plasma half-life ≈ 2.7 h
Frequently asked
How long does PT-141 stay in your system?
With a half-life of ≈ 2.7 h, roughly 97% of a single PT-141 dose is cleared after five half-lives — about 13.5 hours. Repeated dosing accumulates and takes correspondingly longer to clear.
What does a ≈ 2.7 h half-life mean in practice?
Every 2.7 h, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.
Where does this PT-141 half-life number come from?
FDA VYLEESI (bremelanotide) label, NDA 210557 (2019); plasma half-life ≈ 2.7 h. We cite a primary source for every half-life we publish and version every change.
Related: PT-141 reconstitution calculator · PT-141 dose charts
Guides mentioning PT-141
See your own estimated levels
The Zyra Track app plots this curve from the doses you actually log — accumulation, overlaps, and all. Free during the founding period.
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