Congratulations. It is always good to read success stories here.
It has been six months since the first 0.25 mg dose. Starting weight was at least 334 lbs though the exact number was avoided at the time. The current weight is 289 lbs so roughly 45 pounds have come off. That is about a quarter of the total goal. The pace is slower than some because the dose was increased more gradually. The schedule went like this: May at 0.25 mg weekly, June at 0.5 mg, July switched to 0.5 mg of the other compound, August at 1 mg, September at 1 mg of each, October at 1.5 mg and 2 mg, and November planned at 1.5 mg and 3 mg with a possible sema increase to 2 mg. Overall the feeling is quite good and side effects have stayed very light.