Syntax was off in the first post, lol. Just thinking out loud.
Yeah I realize I might be moving too quickly here. What would count as a typical combination for a 53 year old who wants to drop 20 pounds and add some muscle? MD
Users describe their own combinations of retatrutide or tirzepatide with testosterone, tesamorelin, and recovery peptides like BPC-157 or NAD+ for fat loss and body recomposition at similar ages. Several report noticeable improvements in energy, body composition, and food noise control from their stacks, while others stress starting compounds one at a time and pairing any meds with lifting and a modest calorie deficit. Lifestyle habits are repeatedly mentioned as the foundation rather than relying solely on the compounds.
What this discussion establishesWhether adding HGH or several extra peptides is worth the risks versus keeping the stack minimal
Still openLong-term safety and ideal dosing when combining these compounds in people over 50
Nothing here is advice.
Yeah I realize I might be moving too quickly here. What would count as a typical combination for a 53 year old who wants to drop 20 pounds and add some muscle? MD
Syntax was off in the first post, lol. Just thinking out loud.
Reta and test.
From what I have tried, if you have looked into the items, they do not clash with each other, you follow the cycling guidance, and the goal matches, then stacking is fine. I am 33, female, trying to drop 12 kg with three already gone, keep muscle, and recover from daily stress. My current mix is reta, cag, ghk, BPC-157, tb500, kpv, and I am adding nad+ today.
Tirz or Reta, Tesa, and Test Cypionate. I am 52 and that is what I use. I have reached the best shape I have had. Dropped from 208 lb puffy to 187 lb lean in 12 weeks. I also run the KLOW stack for a shoulder issue and general feel.
Reta, tuna fish, and crackers. The holy trinity.
I agree there can be too many. With peptides some treat it like a stack where more is always better. Those same folks often say they are done with polypharmacy. It is the same idea either way, except peptide sources tend to be less reliable.
Thanks, I am pretty much the same way, jump in first and ask later, LOL.
That is hopefully where I will be in six months.
Can you tell me a little about NAD if you have time? What do you think of it, how often do you use it, and at what dose?
It really depends on your starting point, but as a beginner you can lose fat and gain muscle together. Lift heavy, keep a modest deficit, hit about 1 g protein per pound body weight, and aim for 10k steps daily, split across the day. With some help from reta or tirz that is realistic. Use the GLP-1s to shift habits instead of just cutting back on volume of whatever you eat.
I feel really good compared to a month ago. I tried NAD for the first time yesterday and the energy hit right away. I began with a low dose and rate it highly.
Why add cag on top of the reta? What dose of reta are you using?
I am on 2 mg of Reta. The reason I am doing any of this feels like I turned myself into a full science project. I basically ordered what seemed popular online. Right now that adds up to Reta 2 mg started at .5, Tesa 1 mg, IPA/CJ at a ratio I forget, Mots-c 3 mg three days a week, and KLOW .15 after 3 ml reconstitute.
Eli Lilly trials have reta dosing start at 2 mg per week for four weeks, then 4 mg for four, 6 mg for four, 9 mg for four, then 12 mg for four.
My reta dose is 1.5 mg. I only want to lose 10 kg so I am not planning to go much higher, though I may move to 2 mg and stay there. Food noise was very strong for me and with ADHD the urge to eat for dopamine is constant. Adding cag at 0.2 ml helped that a lot. I still eat three meals and hit protein but the constant craving when not hungry is gone.
Goals seem to move in phases. A lot of us start with Reta or another GLP-1 for the initial change. Then we add a GHRH to limit muscle loss and get other benefits. After that come GHK-Cu type peptides for recovery and sometimes BPC/TB/KPV for aches. More active people later add NAD, Mots-C, or 5Amino for workouts. They are not all used at once but rotated as needed.
That lines up with the rough plan I used when deciding what to take, LOL.
Trial schedules aside, I lost my appetite at 3 mg and had to drop back to .5. A friend felt nothing until after six weeks at 3 mg. Start low. You can always add another shot mid-week if needed.
Might be too late, but only add one new item at a time and wait between them. If side effects or an allergy shows up you will not know which caused it, and you also will not know which ones actually helped.
This is all you need. Zippity, feel free to close the thread.
Fair point, but as a recovering alcoholic I am still considering adding NAD, lol. Old habits die hard.
Did adding Cag to your stack reduce food noise for you? I do not respond to Tirz or Reta. I stopped Tirz and am going to try Cag with Reta.
The medication helps with willpower in several ways. Bodybuilding forums show you can bulk or cut. Choose one and try to limit fat gain or muscle loss during that phase.
I am 48 and on Tirz, Growth, test plus regular gym work. I am seeing clear changes in how I look.
Test reta and hgh form my perfect trio.
I have a couple beginner questions. I am only on reta right now, mainly to lose body fat and improve health, but I see many people add HGH. Are there downsides? I prefer fewer compounds and my test levels were normal last check. I used to think HGH meant classic steroid problems like ball shrinkage or hair loss, but it seems that is not the case. Is there good info on this stack, proper dosing, and risks?
Growth is not a steroid. There is a good video on the RP Strength channel about the combination.
There are potential downsides to hgh along with upsides. Peptides, hormones, and steroids are different categories. It comes down to your own risk tolerance. Look up the test and reta info separately. Meso has solid details on that stack. They work well together when dosed right, but I do not really know much, just an octopus, so do not take my word for it.
HGH and secretagogues like tesamorelin have complicated effects, many not well studied long term in humans. The goal is usually less visceral fat and more muscle, though reta already reduces visceral fat well. Side effects can be serious and lasting, so research thoroughly first. Get IGF-1, blood sugar, and HbA1c checked beforehand. Common short-term issues include higher blood sugar, fluid retention with ankle swelling, carpal tunnel, and joint or muscle pain. Longer-term effects in older adults are not studied much because these are not prescribed for general fat loss or muscle gain except in specific medical cases like HIV lipodystrophy. Higher dose or longer use risks include diabetes and acromegaly.
I think I will leave that idea alone for now. It is tempting to try to optimize everything, but I am still getting used to reta by itself. Slow and steady seems better.
To me, hgh is not worth it.
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